Protein Alignment epsilonTry and HGFAC

DIOPT Version :10

• Sequence 1: NP_525112.1
• Gene: epsilonTry / 49080
• FlyBaseID: FBgn0010425
• Length: 256
• Species: Drosophila melanogaster
• Sequence 2: NP_001284368.1
• Gene: HGFAC / 3083
• HGNCID: 4894
• Length: 662
• Species: Homo sapiens
• Alignment Length: 269
• Identity: 77/269 - (28%)
• Similarity: 120/269 - (44%)
• Gaps: 40/269 - (14%)

  Fly    15 LAGTIPDGLLPQ-------------LDGRIVGGYETSIDAHPYQVSLQRYGSHFCGGSIYSHDIV 66
            |..|:|:...|.             |..||:||..:...:||:..::. .|..||.||:.....|
Human   386 LLATLPEPASPGRQACGRRHKKRTFLRPRIIGGSSSLPGSHPWLAAIY-IGDSFCAGSLVHTCWV 449

  Fly    67 ITAAHCLQSIEAKD-LKIRVGSTYWRSGGSVHSVRSFRNHEGYNSRTMVN----DIAIIRIESD- 125
            ::||||......:| :.:.:|..::.....|........:..|...::.|    |:.:||::..
Human   450 VSAAHCFSHSPPRDSVSVVLGQHFFNRTTDVTQTFGIEKYIPYTLYSVFNPSDHDLVLIRLKKKG 514

  Fly   126 --LSFRSS-IREIRIADSNPREGAT------AVVSGWGTTESGGSTIPDHLLAVDLEIIDVSRCR 181
              .:.||. ::.|.:    |..|:|      ..::|||..:...|.....|....:.::...:|.
Human   515 DRCATRSQFVQPICL----PEPGSTFPAGHKCQIAGWGHLDENVSGYSSSLREALVPLVADHKCS 575

  Fly   182 SDEFGYGKKIKDTMLCA--YAPHKDACQGDSGGPLVSGDR----LVGVVSWGYGCGDVRYPGVYA 240
            |.|. ||..|...||||  :....|||||||||||.....    |.|::|||.|||.:..||||.
Human   576 SPEV-YGADISPNMLCAGYFDCKSDACQGDSGGPLACEKNGVAYLYGIISWGDGCGRLHKPGVYT 639

  Fly   241 DVAHFHEWI 249
            .||::.:||
Human   640 RVANYVDWI 648

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
epsilonTry	NP_525112.1	Tryp_SPc	30..249	CDD:214473	70/239 (29%)
HGFAC	NP_001284368.1	PRK14954	<32..>100	CDD:184918
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	64..102
		FN2	102..148	CDD:128373
		EGF_CA	162..197	CDD:238011
		FN1	200..240	CDD:238018
		EGF_CA	245..278	CDD:238011
		Kringle	286..367	CDD:395005
		Tryp_SPc	415..650	CDD:238113	71/240 (30%)