Protein Alignment epsilonTry and HABP2

DIOPT Version :10

• Sequence 1: NP_525112.1
• Gene: epsilonTry / 49080
• FlyBaseID: FBgn0010425
• Length: 256
• Species: Drosophila melanogaster
• Sequence 2: NP_004123.1
• Gene: HABP2 / 3026
• HGNCID: 4798
• Length: 560
• Species: Homo sapiens
• Alignment Length: 290
• Identity: 96/290 - (33%)
• Similarity: 139/290 - (47%)
• Gaps: 56/290 - (19%)

  Fly    10 VLACAL--------AGTIPDGLLPQLDG------------RIVGGYETSIDAHPYQVSLQRY--- 51
            |.||:.        :.|.|...||..|.            ||.||::::...||:|.|||..
Human   273 VSACSAQDVAYPEESPTEPSTKLPGFDSCGKTEIAERKIKRIYGGFKSTAGKHPWQASLQSSLPL 337

  Fly    52 -----GSHFCGGSIYSHDIVITAAHCLQSIEAKDLKIRVGSTYWRSGGSVHSVRSFR-----NHE 106
                 ..|||||::.....|:||||| ..|:.:.||:.:|....:. ...|. :|||     .:.
Human   338 TISMPQGHFCGGALIHPCWVLTAAHC-TDIKTRHLKVVLGDQDLKK-EEFHE-QSFRVEKIFKYS 399

  Fly   107 GYNSRTMV--NDIAIIR---IESDLSFRSS-IREIRIADSNPREGATAVVSGWGTTESG-GSTIP 164
            .||.|..:  ||||:::   ::...:..|. ::.:.:.|.:...|:...:||||.||:| ||.
Human   400 HYNERDEIPHNDIALLKLKPVDGHCALESKYVKTVCLPDGSFPSGSECHISGWGVTETGKGSR-- 462

  Fly   165 DHLLAVDLEIIDVSRCRSDEFGYGKKIKDTMLCA---YAPHKDACQGDSGGPLV---SGDRLV-G 222
             .||...:::|..:.|.|.:. |...|.|:|:||   ..|.:|.|||||||||.   .|...| |
Human   463 -QLLDAKVKLIANTLCNSRQL-YDHMIDDSMICAGNLQKPGQDTCQGDSGGPLTCEKDGTYYVYG 525

  Fly   223 VVSWGYGCGDVRYPGVYADVAHFHEWIERT 252
            :||||..||  :.||||..|..|..||:.|
Human   526 IVSWGLECG--KRPGVYTQVTKFLNWIKAT 553

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
epsilonTry	NP_525112.1	Tryp_SPc	30..249	CDD:214473	85/245 (35%)
HABP2	NP_004123.1	EGF	77..106	CDD:394967
		KR	191..277	CDD:238056	2/3 (67%)
		Tryp_SPc	314..553	CDD:238113	86/247 (35%)