Protein Alignment epsilonTry and TMPRSS12

DIOPT Version :10

• Sequence 1: NP_525112.1
• Gene: epsilonTry / 49080
• FlyBaseID: FBgn0010425
• Length: 256
• Species: Drosophila melanogaster
• Sequence 2: NP_872365.2
• Gene: TMPRSS12 / 283471
• HGNCID: 28779
• Length: 348
• Species: Homo sapiens
• Alignment Length: 268
• Identity: 86/268 - (32%)
• Similarity: 129/268 - (48%)
• Gaps: 54/268 - (20%)

  Fly    17 GTIPDGLLPQLDG-RIVGGYETSIDAHPYQVSLQ-RYGS---HFCGGSIYSHDIVITAAHCLQSI 76
            ||.|  |...|.| ||:||.|....|.|:.|||| :||.   |.|||::.....|:|||||.:
Human    65 GTAP--LKDVLQGSRIIGGTEAQAGAWPWVVSLQIKYGRVLVHVCGGTLVRERWVLTAAHCTK-- 125

  Fly    77 EAKDLKIRVGSTYWRS---GGSVH---------SVRSFRNHEGYNSRTMVNDIAIIRIESDLSFR 129
            :|.|      ...|.:   ..::|         .:::...|..:...:.|||||:..::..:.:.
Human   126 DASD------PLMWTAVIGTNNIHGRYPHTKKIKIKAIIIHPNFILESYVNDIALFHLKKAVRYN 184

  Fly   130 SSIREI-------RIADSNPREGATAVVSGWG-TTESGGSTIPDHLLAVDLEIIDVSR--CRSDE 184
            ..|:.|       :|.|.|.:    ..:|||| |.|.|.:|   ::|. |.|:..:||  |.| |
Human   185 DYIQPICLPFDVFQILDGNTK----CFISGWGRTKEEGNAT---NILQ-DAEVHYISREMCNS-E 240

  Fly   185 FGYGKKIKDTMLCAYAPHK--DACQGDSGGPLV------SGDRLVGVVSWGYGCGDVRYPGVYAD 241
            ..||..|.:|..||.....  |.|:|||||||:      ....::|:.|:|:|||...:||||..
Human   241 RSYGGIIPNTSFCAGDEDGAFDTCRGDSGGPLMCYLPEYKRFFVMGITSYGHGCGRRGFPGVYIG 305

  Fly   242 VAHFHEWI 249
            .:.:.:|:
Human   306 PSFYQKWL 313

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
epsilonTry	NP_525112.1	Tryp_SPc	30..249	CDD:214473	79/252 (31%)
TMPRSS12	NP_872365.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	24..46
		Tryp_SPc	78..316	CDD:238113	79/253 (31%)