Protein Alignment epsilonTry and KLK5

DIOPT Version :10

• Sequence 1: NP_525112.1
• Gene: epsilonTry / 49080
• FlyBaseID: FBgn0010425
• Length: 256
• Species: Drosophila melanogaster
• Sequence 2: NP_036559.1
• Gene: KLK5 / 25818
• HGNCID: 6366
• Length: 293
• Species: Homo sapiens
• Alignment Length: 281
• Identity: 87/281 - (30%)
• Similarity: 133/281 - (47%)
• Gaps: 39/281 - (13%)

  Fly     5 AVLLSVLACALA----------GTIPDGLLPQL-------------DGRIVGGYETSIDAHPYQV 46
            |:||.|....||          .|:|.|....|             ..||:.|.:..:...|:|.
Human    18 ALLLGVTEHVLANNDVSCDHPSNTVPSGSNQDLGAGAGEDARSDDSSSRIINGSDCDMHTQPWQA 82

  Fly    47 S-LQRYGSHFCGGSIYSHDIVITAAHCLQSIEAKDLKIRVG----STYWRSGGSV-HSVRSFRNH 105
            : |.|....:||..:.....::|||||.:.:    .::|:|    |..:.||..: ..|:|. .|
Human    83 ALLLRPNQLYCGAVLVHPQWLLTAAHCRKKV----FRVRLGHYSLSPVYESGQQMFQGVKSI-PH 142

  Fly   106 EGYNSRTMVNDIAIIRIESDLSFRSSIREIRIADSNPREGATAVVSGWGTTESGGSTIPDHLLAV 170
            .||:.....||:.:|::...:.....:|.|.::...|..|...:|||||||:|.....|..|..:
Human   143 PGYSHPGHSNDLMLIKLNRRIRPTKDVRPINVSSHCPSAGTKCLVSGWGTTKSPQVHFPKVLQCL 207

  Fly   171 DLEIIDVSRCRSDEFGYGKKIKDTMLCA-YAPHKDACQGDSGGPLVSGDRLVGVVSWG-YGCGDV 233
            ::.::...||   |..|.::|.|||.|| ....:|:||||||||:|....|.|:|||| |.|...
Human   208 NISVLSQKRC---EDAYPRQIDDTMFCAGDKAGRDSCQGDSGGPVVCNGSLQGLVSWGDYPCARP 269

  Fly   234 RYPGVYADVAHFHEWIERTAE 254
            ..||||.::..|.:||:.|.:
Human   270 NRPGVYTNLCKFTKWIQETIQ 290

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
epsilonTry	NP_525112.1	Tryp_SPc	30..249	CDD:214473	74/226 (33%)
KLK5	NP_036559.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	37..68		5/30 (17%)
		Tryp_SPc	66..285	CDD:214473	74/226 (33%)