Protein Alignment epsilonTry and F10

DIOPT Version :10

• Sequence 1: NP_525112.1
• Gene: epsilonTry / 49080
• FlyBaseID: FBgn0010425
• Length: 256
• Species: Drosophila melanogaster
• Sequence 2: NP_000495.1
• Gene: F10 / 2159
• HGNCID: 3528
• Length: 488
• Species: Homo sapiens
• Alignment Length: 241
• Identity: 88/241 - (36%)
• Similarity: 124/241 - (51%)
• Gaps: 27/241 - (11%)

  Fly    30 RIVGGYETSIDAHPYQVSL-QRYGSHFCGGSIYSHDIVITAAHCLQSIEAKDLKIRVG--STYWR 91
            |||||.|......|:|..| ......||||:|.|...::||||||  .:||..|:|||  :|...
Human   234 RIVGGQECKDGECPWQALLINEENEGFCGGTILSEFYILTAAHCL--YQAKRFKVRVGDRNTEQE 296

  Fly    92 SGG-SVHSVRSFRNHEGYNSRTMVNDIAIIRIESDLSFRSSIR-----EIRIADSNPREGATAVV 150
            .|| :||.|.....|..:...|...|||::|:::.::||.::.     |...|:|......|.:|
Human   297 EGGEAVHEVEVVIKHNRFTKETYDFDIAVLRLKTPITFRMNVAPACLPERDWAESTLMTQKTGIV 361

  Fly   151 SGWGTTESGG--STIPDHLLAVDLEIIDVSRCR-SDEFGYGKKIKDTMLCA-Y-APHKDACQGDS 210
            ||:|.|...|  ||   .|..:::..:|.:.|: |..|    .|...|.|| | ...:|||||||
Human   362 SGFGRTHEKGRQST---RLKMLEVPYVDRNSCKLSSSF----IITQNMFCAGYDTKQEDACQGDS 419

  Fly   211 GGPLVSGDR----LVGVVSWGYGCGDVRYPGVYADVAHFHEWIERT 252
            |||.|:..:    :.|:||||.||......|:|..|..|.:||:|:
Human   420 GGPHVTRFKDTYFVTGIVSWGEGCARKGKYGIYTKVTAFLKWIDRS 465

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
epsilonTry	NP_525112.1	Tryp_SPc	30..249	CDD:214473	85/236 (36%)
F10	NP_000495.1	GLA	25..85	CDD:214503
		EGF_CA	86..122	CDD:238011
		FXa_inhibition	129..164	CDD:464251
		O-glycosylated at one site	183..203
		Tryp_SPc	235..464	CDD:238113	86/237 (36%)
		O-glycosylated at one site	476..485