Protein Alignment epsilonTry and Cfd

DIOPT Version :10

• Sequence 1: NP_525112.1
• Gene: epsilonTry / 49080
• FlyBaseID: FBgn0010425
• Length: 256
• Species: Drosophila melanogaster
• Sequence 2: NP_038487.1
• Gene: Cfd / 11537
• MGIID: 87931
• Length: 259
• Species: Mus musculus
• Alignment Length: 260
• Identity: 78/260 - (30%)
• Similarity: 127/260 - (48%)
• Gaps: 28/260 - (10%)

  Fly     4 FAVLLSVLACALAGTIPDGLLPQLDGRIVGGYETSIDAHPYQVSLQRYGSHFCGGSIYSHDIVIT 68
            :.|.|.:|..|:....|       .|||:||.|.:..|.||..|:|..|:|.|||::.....|::
Mouse     6 YFVALVILGAAVCAAQP-------RGRILGGQEAAAHARPYMASVQVNGTHVCGGTLLDEQWVLS 63

  Fly    69 AAHCLQSIEAKD-LKIRVGS---------TYWRSGGSVHSVRSFRNHEGYNSRTMVNDIAIIRIE 123
            ||||:..:...| :::.:|:         ..|      :.|:|...|.|....::.:|:.:.::.
Mouse    64 AAHCMDGVTDDDSVQVLLGAHSLSAPEPYKRW------YDVQSVVPHPGSRPDSLEDDLILFKLS 122

  Fly   124 SDLSFRSSIR--EIRIADSNPREGATAVVSGWGTTESGGSTIPDHLLAVDLEIIDVSRCRSDEFG 186
            .:.|....:|  .::..|.....|....|:|||.....|.. ||.|..:.:.|::.:.|....:.
Mouse   123 QNASLGPHVRPLPLQYEDKEVEPGTLCDVAGWGVVTHAGRR-PDVLHQLRVSIMNRTTCNLRTYH 186

  Fly   187 YGKKIKDTMLCAYAPHKDACQGDSGGPLVSGDRLVGVVSWGYG-CGDVRYPGVYADVAHFHEWIE 250
            .| .:...|:||.:..:|.|:||||.|||.||.:.|||:||.. ||:.:.||||..|:.:..|||
Mouse   187 DG-VVTINMMCAESNRRDTCRGDSGSPLVCGDAVEGVVTWGSRVCGNGKKPGVYTRVSSYRMWIE 250

  Fly   251  250
            Mouse   251  250

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
epsilonTry	NP_525112.1	Tryp_SPc	30..249	CDD:214473	69/231 (30%)
Cfd	NP_038487.1	Tryp_SPc	26..252	CDD:238113	71/233 (30%)
		Self-inhibitor loop. /evidence=ECO:0000250|UniProtKB:P00746	224..228		2/3 (67%)