Protein Alignment epsilonTry and KLK8

DIOPT Version :9

• Sequence 1: NP_525112.1
• Gene: epsilonTry / 49080
• FlyBaseID: FBgn0010425
• Length: 256
• Species: Drosophila melanogaster
• Sequence 2: NP_653088.1
• Gene: KLK8 / 11202
• HGNCID: 6369
• Length: 305
• Species: Homo sapiens
• Alignment Length: 242
• Identity: 75/242 - (30%)
• Similarity: 117/242 - (48%)
• Gaps: 35/242 - (14%)

  Fly    28 DGRIVGGYETSIDAHPYQVSLQRYGSHFCGGSIYSHDIVITAAHC-------------LQSIEAK 79
            :.:::||:|....:.|:|.:|.:.....|||.:...:.|:|||||             ||:.:..
Human    75 EDKVLGGHECQPHSQPWQAALFQGQQLLCGGVLVGGNWVLTAAHCKKPKYTVRLGDHSLQNKDGP 139

  Fly    80 DLKIRVGSTYWRSGGSVHSVRSFRNHEGYNSRTMV---NDIAIIRIESDLSFRSSIREIRIADSN 141
            :.:|.|          |.|:    .|..|||..:.   :|:.::::....|..|.::.|.:||..
Human   140 EQEIPV----------VQSI----PHPCYNSSDVEDHNHDLMLLQLRDQASLGSKVKPISLADHC 190

  Fly   142 PREGATAVVSGWGTTESGGSTIPDHLLAVDLEIIDVSRCRSDEFGYGKKIKDTMLCA-YAPHKDA 205
            .:.|....||||||..|.....||.|...:::|....:|   |..|..:|.|.|:|| .:...|.
Human   191 TQPGQKCTVSGWGTVTSPRENFPDTLNCAEVKIFPQKKC---EDAYPGQITDGMVCAGSSKGADT 252

  Fly   206 CQGDSGGPLVSGDRLVGVVSWGYG-CGDVRYPGVYADVAHFHEWIER 251
            ||||||||||....|.|:.|||.. ||....||||.::..:.:||::
Human   253 CQGDSGGPLVCDGALQGITSWGSDPCGRSDKPGVYTNICRYLDWIKK 299

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
epsilonTry	NP_525112.1	Tryp_SPc	30..249	CDD:214473	73/236 (31%)
		Tryp_SPc	31..252	CDD:238113	75/239 (31%)
KLK8	NP_653088.1	Tryp_SPc	77..297	CDD:214473	73/236 (31%)
		Tryp_SPc	78..300	CDD:238113	75/239 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm8473
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X21
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.910