Protein Alignment epsilonTry and KLK11

DIOPT Version :10

• Sequence 1: NP_525112.1
• Gene: epsilonTry / 49080
• FlyBaseID: FBgn0010425
• Length: 256
• Species: Drosophila melanogaster
• Sequence 2: XP_011524671.1
• Gene: KLK11 / 11012
• HGNCID: 6359
• Length: 307
• Species: Homo sapiens
• Alignment Length: 281
• Identity: 86/281 - (30%)
• Similarity: 134/281 - (47%)
• Gaps: 47/281 - (16%)

  Fly     7 LLSVLACALAGTIPDGLLPQLDGRIVGGYETSIDAHPYQVSLQRYGSHFCGGSIYSHDIVITAAH 71
            :|.::..|||..:..|     :.||:.|:|....:.|:|.:|.......||.::.:...::||||
Human    35 ILQLILLALATGLVGG-----ETRIIKGFECKPHSQPWQAALFEKTRLLCGATLIAPRWLLTAAH 94

  Fly    72 CLQ--------SIEAKDLKIRVGSTYWRSGGS---VH-----------------SVRSFRNHEGY 108
            ||:        :..:.||.   .|.|..|..|   ||                 :..|| .|.|:
Human    95 CLKPWVSLTSPTHVSPDLS---SSNYCLSHLSRYIVHLGQHNLQKEEGCEQTRTATESF-PHPGF 155

  Fly   109 N----SRTMVNDIAIIRIESDLSFRSSIREIRIADSNPREGATAVVSGWGTTESGGSTIPDHLLA 169
            |    ::...|||.::::.|.:|...::|.:.::......|.:.::||||:|.|....:|..|..
Human   156 NNSLPNKDHRNDIMLVKMASPVSITWAVRPLTLSSRCVTAGTSCLISGWGSTSSPQLRLPHTLRC 220

  Fly   170 VDLEIIDVSRCRSDEFGYGKKIKDTMLCAYAPH--KDACQGDSGGPLVSGDRLVGVVSWGYG-CG 231
            .::.||:..:|   |..|...|.|||:||....  ||:||||||||||....|.|::|||.. |.
Human   221 ANITIIEHQKC---ENAYPGNITDTMVCASVQEGGKDSCQGDSGGPLVCNQSLQGIISWGQDPCA 282

  Fly   232 DVRYPGVYADVAHFHEWIERT 252
            ..|.||||..|..:.:||:.|
Human   283 ITRKPGVYTKVCKYVDWIQET 303

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
epsilonTry	NP_525112.1	Tryp_SPc	30..249	CDD:214473	78/253 (31%)
KLK11	XP_011524671.1	Tryp_SPc	53..300	CDD:214473	78/253 (31%)