DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CSN8 and Cops8

DIOPT Version :9

Sequence 1:	NP_723378.2	Gene:	CSN8 / 49077	FlyBaseID:	FBgn0261437	Length:	182	Species:	Drosophila melanogaster
Sequence 2:	NP_598566.3	Gene:	Cops8 / 108679	MGIID:	1915363	Length:	209	Species:	Mus musculus

Alignment Length:	200	Identity:	54/200 - (27%)
Similarity:	92/200 - (46%)	Gaps:	26/200 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 YSEVVERLENEEFEQVELGA----EVYQQLLAIYLYQNKLADAKLLWMRVPANLRD-DKELIQLN 65
            :.:::::.||:|.|..  |.    .||.||||:||.||.:.:|:.||.|:|..::. :.||..:.
Mouse    13 FRKLLDQCENQELEAP--GGIATPPVYGQLLALYLLQNDMNNARYLWKRIPPAIKSANSELGGIW 75

  Fly    66 LLNIALQNNNYADFFKHIK-YEWSERVKSPVEDLLNKQREELFKLMGSAYMSIYQHNLLELSLMS 129
            .:...:...::...:..|. ::|||.|:..:|.|.:..|...|.|:..||.||...:......:.
Mouse    76 SVGQRIWQRDFPGIYTTINAHQWSETVQPIMEALRDATRRRAFALVSQAYTSIIADDFAAFVGLP 140

  Fly   130 EDELKHACAALNWTEELDGDRVILK----------------PKVQEAP-PARGNDDQLLKLTEFV 177
            .:|.........|..: ...|::|.                |..:.|| |...|:.||.:||::|
Mouse   141 VEEAVKGVLEQGWQAD-STTRMVLPRKPASGTLDVSLNRFIPLSEPAPVPPIPNEQQLARLTDYV 204

  Fly   178 TFLEN 182
            .||||
Mouse   205 AFLEN 209

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CSN8	NP_723378.2	CSN8_PSD8_EIF3K	22..156	CDD:287089	36/155 (23%)
Cops8	NP_598566.3	CSN8_PSD8_EIF3K	34..166	CDD:287089	35/132 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	52	1.000	Domainoid score	I11433
eggNOG	1	0.900	-	-		E1_KOG4414
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H4882
Inparanoid	1	1.050	67	1.000	Inparanoid score	I5334
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG55757
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0005676
OrthoInspector	1	1.000	-	-		oto92428
orthoMCL	1	0.900	-	-		OOG6_104449
Panther	1	1.100	-	-	LDO	PTHR13339
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4524
SonicParanoid	1	1.000	-	-		X4075
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	14	13.860