DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Mbs and Ppp1r27

DIOPT Version :9

Sequence 1:	NP_001246786.1	Gene:	Mbs / 49070	FlyBaseID:	FBgn0005536	Length:	1273	Species:	Drosophila melanogaster
Sequence 2:	NP_001099328.1	Gene:	Ppp1r27 / 287881	RGDID:	1308861	Length:	154	Species:	Rattus norvegicus

Alignment Length:	138	Identity:	53/138 - (38%)
Similarity:	78/138 - (56%)	Gaps:	5/138 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 RAAPTPRHEH---GRRIKFSSGCVFLAACLSGDKDEVVQLL-DQGADINTANVDGLTALHQACID 89
            |.:|..|...   .|.::|.:..:||.....||.::|.:.: .:...::|....||.|||:|.:.
  Rat    10 RYSPRQRRRRLLADRSVRFPNDVLFLDHIRQGDLEQVGRFIRARKVSLDTIYPSGLAALHEAVLS 74

  Fly    90 DNLDMVEFLVERGADINRQDNEGWTPLHATASCGFVSIARYLVENGADVAAVNSDGDLALDLAID 154
            .||:.|:.||:.||||:::|..||||||...|.|:..|||||:..|||..|.|.||||..|| ||
  Rat    75 GNLECVKLLVKYGADIHQRDETGWTPLHIACSDGYPDIARYLISLGADRDATNDDGDLPSDL-ID 138

  Fly   155 VQHMAMID 162
            .....:::
  Rat   139 PDFKDLVE 146

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Mbs	NP_001246786.1	ANK	50..164	CDD:238125	48/114 (42%)
		Ank_2	53..142	CDD:289560	37/89 (42%)
		ANK repeat	78..109	CDD:293786	15/30 (50%)
		ANK	106..290	CDD:238125	27/57 (47%)
		ANK repeat	111..142	CDD:293786	17/30 (57%)
		ANK repeat	209..239	CDD:293786
		Ank_2	213..300	CDD:289560
		ANK repeat	241..272	CDD:293786
		PRKG1_interact	1177..1272	CDD:292521
Ppp1r27	NP_001099328.1	ANK	38..147	CDD:238125	46/110 (42%)
		Ank_2	38..127	CDD:289560	37/88 (42%)
		ANK repeat	63..94	CDD:293786	15/30 (50%)
		ANK repeat	96..127	CDD:293786	17/30 (57%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0505
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810