DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Mbs and LOC101885790

DIOPT Version :9

Sequence 1:	NP_001246786.1	Gene:	Mbs / 49070	FlyBaseID:	FBgn0005536	Length:	1273	Species:	Drosophila melanogaster
Sequence 2:	XP_021325568.1	Gene:	LOC101885790 / 101885790	-ID:	-	Length:	337	Species:	Danio rerio

Alignment Length:	239	Identity:	66/239 - (27%)
Similarity:	115/239 - (48%)	Gaps:	42/239 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly  1056 NSTSNSVSATSANHTTATAPNATSNHDDKDND--KENDN---------RTQTVIQRRRKPKRRST 1109
            |...:|...:|........|:..::...|:::  .||||         ..|.:|:....|
Zfish   110 NPERSSFCMSSVKGACGFTPSLKNHRSLKESEWMDENDNILYGCSGASLAQKLIEDSDLP----- 169

  Fly  1110 GVVHIDMDELDPERQNESSNNDNEEKEKESGSERTSRSRLGSTASTATTSESKSSSSNDKTENGD 1174
            |::         ..|:.:|.:|:      ||.:..| .||.|..||.|..|::.:|.:...|:..
Zfish   170 GLL---------TEQDRASRSDS------SGVDSLS-DRLSSRTSTYTRRENRLASLSKPDEDST 218

  Fly  1175 GIDYKALWEAEKLENDKLRQMLKQKDDEAVQTRATLERFA----NATTKNSLSELEKRERRAMER 1235
            ..|||.|:|....||:||:..|:....|..:.|:.|:|..    ..:.::::.|.||||:.|:|:
Zfish   219 SKDYKKLYEDALSENEKLKSRLEDSKQELTKIRSQLDRVTQKQDRISERSTVFESEKREKEALEK 283

  Fly  1236 KLSELEEELK------QLDAYKSDNHRLKEENAALIRVISKLSK 1273
            ::|::|||||      :|.|.:..|.||..||.|::|.:::||:
Zfish   284 RVSDMEEELKTPPALARLQALRRGNARLLVENKAMLRTLARLSQ 327

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Mbs	NP_001246786.1	ANK	50..164	CDD:238125
		Ank_2	53..142	CDD:289560
		ANK repeat	78..109	CDD:293786
		ANK	106..290	CDD:238125
		ANK repeat	111..142	CDD:293786
		ANK repeat	209..239	CDD:293786
		Ank_2	213..300	CDD:289560
		ANK repeat	241..272	CDD:293786
		PRKG1_interact	1177..1272	CDD:292521	36/104 (35%)
LOC101885790	XP_021325568.1	PRKG1_interact	221..326	CDD:318172	36/104 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	93	1.000	Domainoid score	I7498
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002673
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.910