Protein Alignment NT5E and veil

DIOPT Version :10

• Sequence 1: NP_002517.1
• Gene: NT5E / 4907
• HGNCID: 8021
• Length: 574
• Species: Homo sapiens
• Sequence 2: NP_611217.1
• Gene: veil / 36968
• FlyBaseID: FBgn0034225
• Length: 599
• Species: Drosophila melanogaster
• Alignment Length: 577
• Identity: 230/577 - (39%)
• Similarity: 327/577 - (56%)
• Gaps: 42/577 - (7%)

Human    26 AWELTILHTNDVHSRLEQTSEDSSKC----VNASRCMGGVARLFTKVQQIRR-AEPN---VLLLD 82
            |.|..|||.||:|:|.||||..|..|    .|..:|.||.||:..:|::.|: ||..   |..|:
  Fly    34 AAEFIILHNNDMHARFEQTSVTSGTCSKEEANTDQCYGGFARVAYEVRKYRKEAEEGGTPVFYLN 98

Human    83 AGDQYQGTIWFTVYKGAEVAHFMNALRYDAMALGNHEFDNGVEGLIEPLLKEAKFPILSANIK-- 145
            |||.|.||.||||||....:.|:|.|..||::|||||||..||||: |.|...:||:|:.|:.
  Fly    99 AGDTYTGTAWFTVYKDKIASAFLNKLSPDAISLGNHEFDQNVEGLV-PFLNAVEFPVLACNLNLT 162

Human   146 --AKGPLASQISGLYLPYKVLPVGDEVVGIVGYTSKETPFLSNPGTNLVFEDEITALQPEVDKLK 208
              .:...|.|::.    ..:|......||::||.:.:|..|:. ...:.:|:||.::..|..|||
  Fly   163 DVPEMAAAKQLAN----STILERNGVKVGVIGYLTPDTKVLAF-RNKVEYEEEIVSINAEAAKLK 222

Human   209 TLNVNKIIALGHSGFEMDKLIAQKVRGVDVVVGGHSNTFLYTGNP---PSKEVP---AGKYPFIV 267
            ...:|.||||||||::.|:.||.....||:|:||||:|||....|   |:...|   .|.||..|
  Fly   223 AQGINIIIALGHSGYQKDQEIAMNCPEVDIVIGGHSHTFLDANQPVADPTDSDPEAVRGPYPTTV 287

Human   268 TSDDGRKVPVVQAYAFGKYLGYLKIEFDERGNVISSHGNPILLNSSIPEDPSIKADINKWRIKLD 332
            ....|:|||||||||:.||||.:.::||..||:|...|.|||||:|:.::..:...::::|.|||
  Fly   288 VQASGKKVPVVQAYAYTKYLGKIHVQFDAEGNLIEFDGAPILLNASVAQEQDLLDLLDEYRPKLD 352

Human   333 NYSTQELGKTIVYLDGSSQSCRFRECNMGNLICDAMINNN-LRHTDEMFWNHVSMCILNGGGIRS 396
            ......||.|.|:|:|.: .||.||||:|||:.||||.:. |.:....||...::..:.|||||.
  Fly   353 ELENTVLGYTKVFLEGGN-ICRMRECNLGNLVTDAMIYSRVLENKGGEFWTDTAIAFMQGGGIRG 416

Human   397 PIDERNNGTITWENLAAVLPFGGTFDLVQLKGSTLKKAFEHSVH-RYGQSTGEFLQVGGIHVVYD 460
            .:|::::|.|....|.|||||.....:.::.||||..|.|||.. |...|.|.|||:.|:.|||:
  Fly   417 SVDKKDDGVINGATLLAVLPFENNLYVTRILGSTLLAALEHSASVRLQDSNGGFLQMSGLRVVYN 481

Human   461 LSRKPGDRVVKLDVLCTKCRVPSYDPLKMDEVYKVILPNFLANGGDGFQMIKD-----ELLRHDS 520
            .:.:.|.|||....||..|.||:|..:....:|:||:|.||..||||:.:|::     |.::.:
  Fly   482 YNNEQGKRVVSAQALCASCAVPTYKSINETALYQVIVPQFLLEGGDGYTLIEESDPFTESMQRN- 545

Human   521 GDQDINVVSTYISKMKVIYPAVEGRI----KFSTGSHCH--GSFSLIFLSLWAVIFV 571
               |:|....|:.:...:||.:|.||    |..|||...  .|.||:.||.....|:
  Fly   546 ---DLNATMEYLKQRHFVYPEIEERIVIHEKADTGSASGIVASISLLLLSSLLTRFI 599

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NT5E	NP_002517.1	MPP_CD73_N	29..310	CDD:277354	126/298 (42%)
		5_nucleotid_C	339..513	CDD:427027	75/175 (43%)
veil	NP_611217.1	MPP_CD73_N	37..330	CDD:277354	126/298 (42%)
		5_nucleotid_C	358..534	CDD:427027	75/176 (43%)