Protein Alignment NT5E and CG11883

DIOPT Version :10

• Sequence 1: NP_002517.1
• Gene: NT5E / 4907
• HGNCID: 8021
• Length: 574
• Species: Homo sapiens
• Sequence 2: NP_001097260.1
• Gene: CG11883 / 36121
• FlyBaseID: FBgn0033538
• Length: 792
• Species: Drosophila melanogaster
• Alignment Length: 557
• Identity: 140/557 - (25%)
• Similarity: 250/557 - (44%)
• Gaps: 98/557 - (17%)

Human    29 LTILHTNDVHSRLEQTSEDSSKCVNASRCMGGVARLFTKVQQIRRAEPNVLLLDAGDQYQGTIWF 93
            |||||.|||:: :|..:|        :..:||.||..|.::..  |..|.|:|.:||.:..::..
  Fly   216 LTILHYNDVYN-IESMAE--------TEPVGGAARFATAIKSF--AHLNPLVLFSGDAFSPSMLS 269

Human    94 TVYKGAEVAHFMNALRYDAMALGNHEFDNGVEGLIEPLLKEAKFPILSANI---KAKGPLASQIS 155
            |..:|.::...:|.:.......|||:||:|::.|:: |:|:.:||.|.:|:   :...||.....
  Fly   270 TFTQGEQMIPVLNTVGTHCAVFGNHDFDHGLDVLVK-LIKQTEFPWLMSNVVDNETGRPLGGGKI 333

Human   156 GLYLPYKVLPVGDEVVGIVGYTSKETPFLSNPGTNLVFEDEITALQPEVDKLKTLNVNKIIALGH 220
            ..::.:..:.:|  ::|:|.....||....:| ..:.:.|.:.|......:|:....:.||||.|
  Fly   334 SHFILHNQISIG--LIGLVEREWLETLPTIDP-NEVTYIDYVEAGNKLARELRNEGCDLIIALTH 395

Human   221 SGFEMDKLIAQKVRGVDVVVGGHSNTFLYTGNPPSKEVPAGKYPFIVTSDDGRKVPVVQAYAFGK 285
            .....|..:|:|..|:|:::|||.:.         :|         ||..:|:.  :|::....:
  Fly   396 MRTPNDINLAEKCNGIDIILGGHDHV---------RE---------VTEINGKM--IVKSGTDFQ 440

Human   286 YLGYLKIEFDERGNVISSHGNPIL----LNSSIPEDPSIKADINKWRIKLDNYSTQELGKTIVYL 346
            ....:.||.|....   .|....:    :.:.|||||.:|.:::|:...:::..:..:|...|.|
  Fly   441 QFSVITIERDAANR---EHFTTDVKCFDVTAKIPEDPELKQELSKYAKFIESKLSDVMGVFSVEL 502

Human   347 DGSSQSCRFRECNMGNLICDAMINNNLRHTDEMFWNHVSMCILNGGGIRS----PIDERNNGTIT 407
            ||.....|.:|.|:||.:||.::..          ....:.|||||..||    |:     |..|
  Fly   503 DGRFSRVRTQETNLGNWVCDVVLAA----------VGADVVILNGGTFRSDRVHPV-----GAFT 552

Human   408 WENLAAVLPFGGTFDLVQLKGSTLKKAFEHSVHRYGQSTGEFLQVGGIHVVYDLSRKPGDRVVKL 472
            ..:|..|:|......|:::||..|.:|.|:.|..|.:..|.|.||.||...:|...:||.|:
  Fly   553 MGDLVNVIPMRDPLILLEVKGKILWQALENGVSAYPKLEGRFPQVSGISFAFDPQAEPGKRI--- 614

Human   473 DVLCTKCRVPSYDP---------LKMDEVYKVILPNFLANGGDGFQMIKD-ELLRHDSGDQDINV 527
                        ||         |.:::.||:.:.:::..|.||:.|.|| .:|..|....::.:
  Fly   615 ------------DPQLIQVGDEYLNLEQSYKLCVKSYIFMGCDGYTMFKDATVLMDDDACPELGI 667

Human   528 VSTYISKMKVIYPAVEGRIKFSTGSHCHGSFSLIFLS 564
            .      ::..:.|:..|   ..|.:.....||:.||
  Fly   668 T------LQNHFKAINSR---KCGQNTKHRQSLVTLS 695

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NT5E	NP_002517.1	MPP_CD73_N	29..310	CDD:277354	70/287 (24%)
		5_nucleotid_C	339..513	CDD:427027	52/186 (28%)
CG11883	NP_001097260.1	MPP_CG11883_N	216..473	CDD:277351	72/294 (24%)
		5_nucleotid_C	494..652	CDD:427027	52/187 (28%)