Protein Alignment NT5E and CG42249

DIOPT Version :10

• Sequence 1: NP_002517.1
• Gene: NT5E / 4907
• HGNCID: 8021
• Length: 574
• Species: Homo sapiens
• Sequence 2: NP_572684.2
• Gene: CG42249 / 32043
• FlyBaseID: FBgn0259101
• Length: 558
• Species: Drosophila melanogaster
• Alignment Length: 556
• Identity: 181/556 - (32%)
• Similarity: 302/556 - (54%)
• Gaps: 29/556 - (5%)

Human    12 LLLALGAVLWPAAGA-----WELTILHTNDVHSRLEQTSEDSSKCVNASRCMGGVARLFTKVQQI 71
            :::|:.||:..:|.|     :.:.|:|.||:|:|.|.|......|.....|:||..|....|:::
  Fly    14 VVVAVMAVMCSSAEAADKEGFPVAIIHINDLHARFEATDTSGGTCDEGEECIGGYPRTVYTVKRL 78

Human    72 --RRAEPNVLLLDAGDQYQGTIWFTVYKGAEVAHFMNALRYDAMALGNHEFDNGVEGLIEPLLKE 134
              .:||.|.:.::|||.:|||:|:.:.:.......:|.|..|.|.|||||||:||||:: |.|:.
  Fly    79 LQEQAELNPIYINAGDSFQGTLWYNIGRWNVTQQLLNLLPADVMTLGNHEFDHGVEGVV-PFLET 142

Human   135 AKFPILSANIK-AKGPLASQISGLYLPYKVLPVGDEVVGIVGYTSKETPFLSNPGTNLVFEDEIT 198
            ....:|.||:. |..|   .:.|.|....::......:|::|...:.|..|:|.| .::|.:|..
  Fly   143 VDTNMLVANMDCAHEP---TMEGKYNKSMIIERSGRKIGVIGVILETTYDLANTG-KVIFRNESD 203

Human   199 ALQPEVDKLKTLNVNKIIALGHSGFEMDKLIAQKVRG-VDVVVGGHSNTFLYTGNPPSKEVPAGK 262
            .::.|...||....|.||.:.|.|:::|:.||..... :||:||.||:||||||:||....|:|.
  Fly   204 TIREEAQLLKAQGANIIIVVSHCGYDVDQQIAANAGDWIDVIVGSHSHTFLYTGDPPGPHTPSGD 268

Human   263 YPFIVTSDDGRKVPVVQAYAFGKYLGYLKIEFDERGNVISSHGNPILLNSSIPEDPSIKADINKW 327
            ||..|....|.:|.:|||.|:.:|:|.|.:.||:.|:|:...|:|:.::.|:|||..:...:..|
  Fly   269 YPTEVIHSSGHRVLIVQASAYARYVGNLIVYFDDNGDVLDYEGDPLYMDQSVPEDDIVLQAMVPW 333

Human   328 RIKLDNYSTQELGKTIVYLDGSSQSCRFRECNMGNLICDAMIN---NNLRHTDEMFWNHVSMCIL 389
            ::::...:.:.:|::.|.|..|  .|...|||:||...|||::   .:...:.|..|::|::.:.
  Fly   334 QLEMKPIAERTVGQSRVNLQQS--QCSSGECNLGNFFTDAMLHAFVKDASSSSEESWSNVTIALT 396

Human   390 NGGGIRSPIDERNNGTITWENLAAVLPFGGTFDLVQLKGSTLKKAFEHSVHRYGQS-----TGEF 449
            :.|..|.||..   |.||::.|.|:.|:......:.|:|..:.:..||.|.....|     :..|
  Fly   397 STGTFRVPIPA---GNITYKQLFAMCPWQNRLVTLSLRGKHIVELLEHVVAPMNASSATPRSSRF 458

Human   450 LQVGGIHVVYDLSRKPGDRVVKLDVLCTKCRVPSYDPLKMDEVYKVILPNFLANGGDGFQMIKDE 514
            |||.|:.:.|||:  ...||..:.|.|:||.||.|.||.::..|:|::..:||||.:||.:|.:.
  Fly   459 LQVSGLRIRYDLN--ADQRVFSVRVRCSKCLVPRYIPLDLEHKYRVVVMEYLANGKNGFSVISEN 521

Human   515 LLRHDSGDQDINVVSTYISKMKVIYPAVEGRIKFST 550
            ....:.|..|::.:..|::....|..|:|.||:|.|
  Fly   522 AEDPEFGPFDLDALMDYMNSTGPITTAIEQRIQFVT 557

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NT5E	NP_002517.1	MPP_CD73_N	29..310	CDD:277354	101/284 (36%)
		5_nucleotid_C	339..513	CDD:427027	60/181 (33%)
CG42249	NP_572684.2	MPP_CD73_N	36..316	CDD:277354	101/284 (36%)
		5_nucleotid_C	345..520	CDD:427027	60/181 (33%)