Protein Alignment NSF and nsfa

DIOPT Version :10

• Sequence 1: NP_006169.2
• Gene: NSF / 4905
• HGNCID: 8016
• Length: 744
• Species: Homo sapiens
• Sequence 2: XP_021325418.1
• Gene: nsfa / 368483
• ZFINID: ZDB-GENE-030616-37
• Length: 747
• Species: Danio rerio
• Alignment Length: 738
• Identity: 641/738 - (86%)
• Similarity: 699/738 - (94%)
• Gaps: 0/738 - (0%)

Human     1 MAGRSMQAARCPTDELSLTNCAVVNEKDFQSGQHVIVRTSPNHRYTFTLKTHPSVVPGSIAFSLP 65
            ||.|:|||||||||||||||||||:|||.||||||.|||:|.|::.||:|.|.||:||:||||||
Zfish     1 MATRTMQAARCPTDELSLTNCAVVSEKDLQSGQHVTVRTTPTHKFVFTVKGHHSVLPGTIAFSLP 65

Human    66 QRKWAGLSIGQEIEVSLYTFDKAKQCIGTMTIEIDFLQKKSIDSNPYDTDKMAAEFIQQFNNQAF 130
            ||||||||||||||||.|.|||::||||.||||||||||||.||:|||:|||||||||.||||:|
Zfish    66 QRKWAGLSIGQEIEVSNYNFDKSRQCIGAMTIEIDFLQKKSTDSSPYDSDKMAAEFIQHFNNQSF 130

Human   131 SVGQQLVFSFNEKLFGLLVKDIEAMDPSILKGEPATGKRQKIEVGLVVGNSQVAFEKAENSSLNL 195
            ||||||||||.:||||||:|||||||.||||||||:||:|||||||:||||||.|||:|:|||.|
Zfish   131 SVGQQLVFSFCDKLFGLLIKDIEAMDSSILKGEPASGKKQKIEVGLLVGNSQVIFEKSESSSLTL 195

Human   196 IGKAKTKENRQSIINPDWNFEKMGIGGLDKEFSDIFRRAFASRVFPPEIVEQMGCKHVKGILLYG 260
            :|||||||.||:|||||||||||||||||||||||||||||||||||:|||||||||||||||:|
Zfish   196 VGKAKTKEARQTIINPDWNFEKMGIGGLDKEFSDIFRRAFASRVFPPDIVEQMGCKHVKGILLFG 260

Human   261 PPGCGKTLLARQIGKMLNAREPKVVNGPEILNKYVGESEANIRKLFADAEEEQRRLGANSGLHII 325
            ||||||||:||||||||||||||:|||||||||||||||||||||||||||||:|||||||||||
Zfish   261 PPGCGKTLMARQIGKMLNAREPKIVNGPEILNKYVGESEANIRKLFADAEEEQKRLGANSGLHII 325

Human   326 IFDEIDAICKQRGSMAGSTGVHDTVVNQLLSKIDGVEQLNNILVIGMTNRPDLIDEALLRPGRLE 390
            ||||:||||||||:.|.|||||||||||||||||||||||||||||||||||||||||:||||.|
Zfish   326 IFDELDAICKQRGTGASSTGVHDTVVNQLLSKIDGVEQLNNILVIGMTNRPDLIDEALMRPGRFE 390

Human   391 VKMEIGLPDEKGRLQILHIHTARMRGHQLLSADVDIKELAVETKNFSGAELEGLVRAAQSTAMNR 455
            |||||||||||||:|||:||||:||..:||::|||:||||.||||:|||||||||||||||||||
Zfish   391 VKMEIGLPDEKGRVQILNIHTAKMREFKLLASDVDVKELAAETKNYSGAELEGLVRAAQSTAMNR 455

Human   456 HIKASTKVEVDMEKAESLQVTRGDFLASLENDIKPAFGTNQEDYASYIMNGIIKWGDPVTRVLDD 520
            ||||::.||||||:||.|||||.||:|||.||||||||||||||:||||||||||||||||||:|
Zfish   456 HIKATSTVEVDMERAEKLQVTRTDFMASLNNDIKPAFGTNQEDYSSYIMNGIIKWGDPVTRVLED 520

Human   521 GELLVQQTKNSDRTPLVSVLLEGPPHSGKTALAAKIAEESNFPFIKICSPDKMIGFSETAKCQAM 585
            ||||||||||||||||||||||||||||||||||||:|:|.||||||||||||||.||.:||||:
Zfish   521 GELLVQQTKNSDRTPLVSVLLEGPPHSGKTALAAKISEDSQFPFIKICSPDKMIGHSEISKCQAI 585

Human   586 KKIFDDAYKSQLSCVVVDDIERLLDYVPIGPRFSNLVLQALLVLLKKAPPQGRKLLIIGTTSRKD 650
            |||||||||||||||||||||||||||||||||||||||||||||||.||.||||||||||||||
Zfish   586 KKIFDDAYKSQLSCVVVDDIERLLDYVPIGPRFSNLVLQALLVLLKKTPPHGRKLLIIGTTSRKD 650

Human   651 VLQEMEMLNAFSTTIHVPNIATGEQLLEALELLGNFKDKERTTIAQQVKGKKVWIGIKKLLMLIE 715
            ||||||||:||||||||.||::|:.|:|||||||:|.|.|||||||.||||:|||||||||||||
Zfish   651 VLQEMEMLDAFSTTIHVQNISSGDHLVEALELLGSFTDAERTTIAQHVKGKRVWIGIKKLLMLIE 715

Human   716 MSLQMDPEYRVRKFLALLREEGA 738
            ||||||.||||.|||:||::|||
Zfish   716 MSLQMDQEYRVSKFLSLLKDEGA 738

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NSF	NP_006169.2	CDC48_N	6..83	CDD:215012	63/76 (83%)
		CDC48_2	111..183	CDD:215011	61/71 (86%)
		CDC48	159..>606	CDD:273521	397/446 (89%)
		RecA-like_NSF-SEC18_r1-like	219..395	CDD:410912	164/175 (94%)
nsfa	XP_021325418.1	CDC48_N	5..85	CDD:426738	64/79 (81%)
		CDC48_2	111..183	CDD:215011	61/71 (86%)
		CDC48	160..>606	CDD:273521	396/445 (89%)
		RecA-like_NSF-SEC18_r1-like	219..395	CDD:410912	164/175 (94%)