Protein Alignment NSF and TER94

DIOPT Version :10

• Sequence 1: NP_006169.2
• Gene: NSF / 4905
• HGNCID: 8016
• Length: 744
• Species: Homo sapiens
• Sequence 2: NP_001097249.1
• Gene: TER94 / 36040
• FlyBaseID: FBgn0286784
• Length: 826
• Species: Drosophila melanogaster
• Alignment Length: 556
• Identity: 168/556 - (30%)
• Similarity: 263/556 - (47%)
• Gaps: 112/556 - (20%)

Human   189 ENSSLNLIGKAKTKENRQSIINPDWNFEKMGIGGLDKEFSDIFRRAFASRVFPPEIVEQMGCKHV 253
            |..|||.:|..                   .|||..|:.:.| :......:..|.:.:.:|.|..
  Fly   216 EEESLNAVGYD-------------------DIGGCRKQLAQI-KEMVELPLRHPSLFKAIGVKPP 260

Human   254 KGILLYGPPGCGKTLLARQIGKMLNAREPK----VVNGPEILNKYVGESEANIRKLFADAEEEQR 314
            :|||:|||||.||||:||.:     |.|..    ::|||||::|..||||:|:||.|.:||:
  Fly   261 RGILMYGPPGTGKTLIARAV-----ANETGAFFFLINGPEIMSKLAGESESNLRKAFEEAEK--- 317

Human   315 RLGANSGLHIIIFDEIDAICKQRGSMAGSTGVHDTVVNQLLSKIDGVEQLNNILVIGMTNRPDLI 379
                ||.. ||..||||||..:|....|.  |...:|:|||:.:||:::.::::|:..||||:.|
  Fly   318 ----NSPA-IIFIDEIDAIAPKRDKTHGE--VERRIVSQLLTLMDGMKKSSHLIVMAATNRPNSI 375

Human   380 DEALLRPGRLEVKMEIGLPDEKGRLQILHIHTARMRGHQLLSADVDIKELAVETKNFSGAELEGL 444
            |.||.|.||.:.:::||:||..|||::|.|||..|:.|.    |||::::|.|:....||:|..|
  Fly   376 DPALRRFGRFDREIDIGIPDATGRLEVLRIHTKNMKLHD----DVDLEQIAAESHGHVGADLASL 436

Human   445 VRAAQSTAMNRHIKASTKV------EVDMEKAESLQVTRGDFL--------ASLENDIKPAFGTN 495
            .    |.|..:.|:....:      ::|.|...||.||..:|.        ::|...:.....|.
  Fly   437 C----SEAALQQIREKMDLIDLEDDKIDAEVLASLAVTMENFRYAMTKSSPSALRETVVEVPNTT 497

Human   496 QEDYASYIMNGIIKWGDPVTRVLDDGELLVQQTKNSDR------TPLVSVLLEGPPHSGKTALAA 554
            ..|     :.|:    :.|.:.|.  ||:....::.|:      .|...||..|||..|||.||.
  Fly   498 WTD-----IGGL----ESVKKELQ--ELVQYPVEHPDKFLKFGMQPSRGVLFYGPPGCGKTLLAK 551

Human   555 KIAEESNFPFIKICSPDKM---IGFSETAKCQAMKKIFDDAYKSQLSCVV-VDDIERLL------ 609
            .||.|....||.:..|:.:   .|.||.    .::.|||.| :|...||: .|:::.:.
  Fly   552 AIANECQANFISVKGPELLTMWFGESEA----NVRDIFDKA-RSAAPCVLFFDELDSIAKARGGN 611

Human   610 --DYVPIGPRFSNLVLQALLVLLKKAPPQGRKLLIIGTTSRKDVLQ-------EMEMLNAFSTTI 665
              |......|..|.:|..:..:..|     :.:.|||.|:|.|::.       .::.|    ..|
  Fly   612 VGDAGGAADRVINQILTEMDGMGAK-----KNVFIIGATNRPDIIDPAILRPGRLDQL----IYI 667

Human   666 HVPNIATGEQLLEA-LELLGNFKDKERTTIAQQVKG 700
            .:|:..:.|.:|:| |......|:.:.|.||:..:|
  Fly   668 PLPDDKSREAILKANLRKSPLAKEVDLTYIAKVTQG 703

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NSF	NP_006169.2	CDC48_N	6..83	CDD:215012
		CDC48_2	111..183	CDD:215011
		CDC48	159..>606	CDD:273521	145/444 (33%)
		RecA-like_NSF-SEC18_r1-like	219..395	CDD:410912	71/179 (40%)
TER94	NP_001097249.1	CDC48	47..787	CDD:273521	168/556 (30%)