DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment NSF and CG5776

DIOPT Version :10

Sequence 1:NP_006169.2 Gene:NSF / 4905 HGNCID:8016 Length:744 Species:Homo sapiens
Sequence 2:NP_609585.1 Gene:CG5776 / 34680 FlyBaseID:FBgn0032450 Length:799 Species:Drosophila melanogaster


Alignment Length:373 Identity:114/373 - (30%)
Similarity:185/373 - (49%) Gaps:77/373 - (20%)


- Green bases have known domain annotations that are detailed below.


Human   152 IEAMDPSILK----------GEPATGKRQKIEVGLVVG-NSQVAFEKAENSS-----------LN 194
            |:.:.|||.:          |.|::..|.:|...|:.. ..|::.|:.|:.:           .|
  Fly   427 IDTLHPSIRRAGRLDNEVELGAPSSQARLEIVRCLIKSVEHQLSDEEVEHVASITHGYVGADLAN 491

Human   195 LIGKA---------------------KTKENRQSII---NPDWNFEKMGIGGLDKEFSDIFRRAF 235
            |:..|                     |....|:.:|   |..|:    .||| ..|.....::|.
  Fly   492 LVYAAMLQAQPNPLQMPHLQAALTRIKPSAMREVLIECPNVQWS----DIGG-QSELRLAMQQAI 551

Human   236 ASRVFPPEIVEQMGCKHVKGILLYGPPGCGKTLLARQIGKMLNAREPKV----VNGPEILNKYVG 296
            ...:...:..:::|.|..:|||::|||||.||::|:.:     |.|.|:    :.|||:.:.:||
  Fly   552 EWPLLHADKFQRLGIKPPRGILMFGPPGCSKTMIAKAL-----ATESKLNFLSIKGPELFSMWVG 611

Human   297 ESEANIRKLFADAEEEQRRLGANSGLHIIIFDEIDAICKQR----GSMAGSTGVHDTVVNQLLSK 357
            |||..:|::|..|.:....        |:.|||||||..:|    ||.:||: |.:.|:.|||::
  Fly   612 ESERAVREVFRKARQVAPA--------IVFFDEIDAIGGERSEGDGSSSGSS-VKERVLTQLLTE 667

Human   358 IDGVEQLNNILVIGMTNRPDLIDEALLRPGRLEVKMEIGLPDEKGRLQILHIHTARMRGHQLLSA 422
            :||||.|.|:.::..|||||:||:|||||||::..:.:|||..:.|.:||.|....|.    :|.
  Fly   668 LDGVEALQNVTIVAATNRPDMIDKALLRPGRIDRILYVGLPQCEARREILKIKLRAMP----ISN 728

Human   423 DVDIKELAVETKNFSGAELEGLVRAAQSTAMNRHIKASTKVEVDMEKA 470
            |||:::|...|:.:||||::.:...|...|:.:..:|......|.|.|
  Fly   729 DVDMEKLVQLTEGYSGAEIQAVCHEAALRALEQSFEAEDVKWTDFEHA 776

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
NSFNP_006169.2 CDC48_N 6..83 CDD:215012
CDC48_2 111..183 CDD:215011 9/41 (22%)
CDC48 159..>606 CDD:273521 111/366 (30%)
RecA-like_NSF-SEC18_r1-like 219..395 CDD:410912 70/183 (38%)
CG5776NP_609585.1 CDC48 183..797 CDD:273521 114/373 (31%)
Blue background indicates that the domain is not in the aligned region.

Return to query results.
Submit another query.