DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Gprk2 and PK1

DIOPT Version :9

Sequence 1:	NP_001263143.1	Gene:	Gprk2 / 49045	FlyBaseID:	FBgn0261988	Length:	714	Species:	Drosophila melanogaster
Sequence 2:	NP_001326081.1	Gene:	PK1 / 820020	AraportID:	AT3G08730	Length:	465	Species:	Arabidopsis thaliana

Alignment Length:	288	Identity:	109/288 - (37%)
Similarity:	171/288 - (59%)	Gaps:	12/288 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly   309 FRMYRVLGKGGFGEVCACQVRATGKMYACKKLEKKRIKKRKGESMVLIEKQILQKINSPFVVNLA 373
            |.:.:|:|||.||:|...:.:.|.::||.|.:.|..|.::.....:..|:.||.||:.||:|.|.
plant   134 FEVMKVVGKGAFGKVYQVRKKETSEIYAMKVMRKDHIMEKNHAEYMKAERDILTKIDHPFIVQLK 198

  Fly   374 YAYETKDALCLVLTIMNGGDLKFHIYNMGGEPGFELERARFYAAEVACGLQHLHKQGIVYRDCKP 438
            |:::||..|.|||..:|||.|.|.:|:.|   .|..:.||.|.||:...:.|||::||::||.||
plant   199 YSFQTKYRLYLVLDFINGGHLFFQLYHQG---LFREDLARVYTAEIVSAVSHLHEKGIMHRDLKP 260

  Fly   439 ENILLDDHGHVRISDLGLAVEIPEGEMVRGRVGTVGYMAPEVIDNEKYAFSPDWFSFGCLLYEMI 503
            ||||:|..|||.::|.|||.|..|........||..|||||::..:.:..:.||:|.|.|||||:
plant   261 ENILMDTDGHVMLTDFGLAKEFEENTRSNSMCGTTEYMAPEIVRGKGHDKAADWWSVGILLYEML 325

  Fly   504 EGQAPFRMRKEKVKREEVDRRVKEDPEKYSSKFNDEAKSMCQQLLAKSIKQRLGCRNGRMGGQDV 568
            .|:.||...|.|::     :::.:|..|.....::||.::.:.||.|..::|||  :|..|.:::
plant   326 TGKPPFLGSKGKIQ-----QKIVKDKIKLPQFLSNEAHAILKGLLQKEPERRLG--SGLSGAEEI 383

  Fly   569 MAHPFFHSTQLNWRRLEAGMLEPPFVPD 596
            ..|.:|..  :||::|||..:.|.|.|:
plant   384 KQHKWFKG--INWKKLEAREVMPSFKPE 409

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Gprk2	NP_001263143.1	RGS	35..>111	CDD:295367
		RGS	<248..305	CDD:295367
		STKc_GRK4_like	308..597	CDD:270756	109/288 (38%)
		S_TKc	309..574	CDD:214567	100/264 (38%)
PK1	NP_001326081.1	STKc_AGC	140..389	CDD:270693	98/258 (38%)
PK1	NP_001326081.1	S_TK_X	390..452	CDD:214529	8/22 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910