DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Gprk2 and sgk1

DIOPT Version :9

Sequence 1:	NP_001263143.1	Gene:	Gprk2 / 49045	FlyBaseID:	FBgn0261988	Length:	714	Species:	Drosophila melanogaster
Sequence 2:	XP_012818527.1	Gene:	sgk1 / 594981	XenbaseID:	XB-GENE-1003518	Length:	434	Species:	Xenopus tropicalis

Alignment Length:	290	Identity:	107/290 - (36%)
Similarity:	159/290 - (54%)	Gaps:	14/290 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly   309 FRMYRVLGKGGFGEVCACQVRATGKMYACKKLEKKRIKKRKGESMVLIEKQILQK-INSPFVVNL 372
            |:..:::|||.||:|...:..|..|.||.|.|:||.|.|:|.|..::.|:.:|.| :..||:|.|
Frog   101 FQFLKIIGKGSFGKVLLARHNADEKFYAVKVLQKKAILKKKEEKHIMSERNVLLKNVKHPFLVGL 165

  Fly   373 AYAYETKDALCLVLTIMNGGDLKFHIYNMGGEPGFELERARFYAAEVACGLQHLHKQGIVYRDCK 437
            .::::|...|..:|..:|||:|.:|:..   |..|...||||||||:|..|.:||...|||||.|
Frog   166 HFSFQTTSRLYFILDYINGGELFYHLQR---ERCFLEPRARFYAAEIASALGYLHSLNIVYRDLK 227

  Fly   438 PENILLDDHGHVRISDLGLAVE-IPEGEMVRGRVGTVGYMAPEVIDNEKYAFSPDWFSFGCLLYE 501
            |||||||..||:.::|.||..| |..........||..|:||||:..:.|..:.||:..|.:|||
Frog   228 PENILLDSQGHIILTDFGLCKENIEPNGTTSTFCGTPEYLAPEVLHKQPYDRTVDWWCLGAVLYE 292

  Fly   502 MIEGQAPFRMRKEKVKREEVDRRVKEDPEKYSSKFNDEAKSMCQQLLAKSIKQRLGCRNGRMGGQ 566
            |:.|..||..|    ...|:...:...|.:......:.|:::.:.||.|...:|:|.:|..|
Frog   293 MLYGLPPFYSR----NTAEMYDNILNKPLQLKPNITNSARNLLEGLLQKDRTKRIGAKNDFM--- 350

  Fly   567 DVMAHPFFHSTQLNWRRLEAGMLEPPFVPD 596
            ::..|.||  :.:||..|....:.|||.|:
Frog   351 EIKNHMFF--SPINWDDLINKKITPPFNPN 378

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Gprk2	NP_001263143.1	RGS	35..>111	CDD:295367
		RGS	<248..305	CDD:295367
		STKc_GRK4_like	308..597	CDD:270756	107/290 (37%)
		S_TKc	309..574	CDD:214567	98/266 (37%)
sgk1	XP_012818527.1	STKc_SGK1	93..431	CDD:270753	107/290 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910