Protein Alignment Gprk2 and grk7a

DIOPT Version :9

• Sequence 1: NP_001263143.1
• Gene: Gprk2 / 49045
• FlyBaseID: FBgn0261988
• Length: 714
• Species: Drosophila melanogaster
• Sequence 2: NP_001027011.2
• Gene: grk7a / 566120
• ZFINID: ZDB-GENE-050824-1
• Length: 549
• Species: Danio rerio
• Alignment Length: 655
• Identity: 250/655 - (38%)
• Similarity: 354/655 - (54%)
• Gaps: 139/655 - (21%)

  Fly     3 LENIVANTVYLKAREGGSDSNKGKSKKWRKILQFPHISQCINLKDKLDISYGYVIDQQPIGRELF 67
            |:|:||||.|||| :||.|.   :.||.|:.|..|...||.:|:..||..:..:.::||||::||
Zfish     7 LDNLVANTAYLKA-QGGDDK---EMKKRRRSLSLPKPEQCASLRTSLDKDFESLCEKQPIGKKLF 67

  Fly    68 RLFCENKRPVYFRYITFLDEVVKYEIEYISNRIFIGHDIGRRFLDVEAQLELRNGSGGDALDAET 132
            |.:.....|.......|||::.::|:
Zfish    68 RQYLSQGGPECTTAAEFLDDLNEWEL--------------------------------------- 93

  Fly   133 QEELLLNSSNANPTETAETEHCNNTTANNCNNINNSNNSQHSSDINHKKLDTRNHNGDDATGNGS 197
                    |.:...:.|.|           |.||..
Zfish    94 --------SESAARDKART-----------NIINKF----------------------------- 110

  Fly   198 SHQDDGDESVKCQEGHDDAEKGGGGEGGGGGKCVPVGGYPDELVLDVLNDDLIAQVRNKLNSGGK 262
                       |:||...:                         |..|..|:..:.:...:...:
Zfish   111 -----------CKEGSKSS-------------------------LTFLTGDVATKCKAVSDKDFE 139

  Fly   263 DIFAQCVNAVKAFLAGEPFREFESSMYFHRYLQWKWLEAQPITYKTFRMYRVLGKGGFGEVCACQ 327
            ::..|...|.|.||.|:||.|:::|.:|.::||||..|.|||:.|.|..:|.|||||||||||.|
Zfish   140 EVMGQVKTATKEFLKGKPFTEYQASPFFDKFLQWKEYEKQPISEKYFYEFRTLGKGGFGEVCAVQ 204

  Fly   328 VRATGKMYACKKLEKKRIKKRKGESMVLIEKQILQKINSPFVVNLAYAYETKDALCLVLTIMNGG 392
            |:.||:|||||||.|||:||:.||.|.|:||:||:::||.|:|:|||||:||..||||:::||||
Zfish   205 VKNTGQMYACKKLCKKRLKKKHGEKMALLEKKILERVNSLFIVSLAYAYDTKTHLCLVMSLMNGG 269

  Fly   393 DLKFHIYNMGGEPGFELERARFYAAEVACGLQHLHKQGIVYRDCKPENILLDDHGHVRISDLGLA 457
            |||:||||: ||.|.|::|..:|.|::|.|:.|||...|||||.||||:|||..|..|:||||||
Zfish   270 DLKYHIYNI-GEKGIEMDRIIYYTAQIATGILHLHDMDIVYRDMKPENVLLDSQGQCRLSDLGLA 333

  Fly   458 VEIPEGEMVRGRVGTVGYMAPEVIDNEKYAFSPDWFSFGCLLYEMIEGQAPFR---MRKEKVKRE 519
            |||..|:.:..:.||..|||||:::...|..|.||::.||.:|||:.|..||:   .:||||::|
Zfish   334 VEIAVGKTISQKAGTGAYMAPEILNETPYRTSVDWWALGCSIYEMVAGYTPFKGPDAKKEKVEKE 398

  Fly   520 EVDRRVKEDPEKYSSKFNDEAK-SMCQQLLAKSIKQRLGCRNGRMGGQDVMAHPFFHSTQLNWRR 583
            ||.||:..:..|:..|..|.|. .:.:|.|.|.|.:||||:|     .|...|.:|.|  :|:.|
Zfish   399 EVQRRILNEEPKFEHKNFDAATIDIIKQFLKKKIDERLGCKN-----DDPRKHEWFKS--INFAR 456

  Fly   584 LEAGMLEPPFVPDPHAVYAKDVLDIEQFSTVKGVNIDESDTNFYTKFNTGSVSISWQNEMMETEC 648
            ||||:::||:||.|:.|||||..||.:||.:||:..|..|..|:.:|:||:|||:||.||::|..
Zfish   457 LEAGLIDPPWVPKPNVVYAKDTGDIAEFSEIKGIEFDAKDDKFFKEFSTGAVSIAWQQEMIDTGL 521

  Fly   649 FRELN 653
            |.||:
Zfish   522 FDELS 526

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gprk2	NP_001263143.1	RGS	35..>111	CDD:295367	18/75 (24%)
		RGS	<248..305	CDD:295367	19/56 (34%)
		STKc_GRK4_like	308..597	CDD:270756	154/292 (53%)
		S_TKc	309..574	CDD:214567	142/268 (53%)
grk7a	NP_001027011.2	RGS_GRK7	37..176	CDD:188703	45/261 (17%)
		PKc_like	183..469	CDD:389743	154/293 (53%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	522..549		3/5 (60%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0986
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1104340at2759
OrthoFinder	1	1.000	-	-		FOG0001059
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24355
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	6	5.920