DRSC/TRiP Functional Genomics Resources

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Protein Alignment Gprk2 and prkacaa

DIOPT Version :9

Sequence 1:NP_001263143.1 Gene:Gprk2 / 49045 FlyBaseID:FBgn0261988 Length:714 Species:Drosophila melanogaster
Sequence 2:XP_021326630.1 Gene:prkacaa / 564064 ZFINID:ZDB-GENE-050114-6 Length:389 Species:Danio rerio


Alignment Length:479 Identity:125/479 - (26%)
Similarity:216/479 - (45%) Gaps:103/479 - (21%)


- Green bases have known domain annotations that are detailed below.


  Fly   184 TRNHNGD-DATGNGSSHQDDGDESVKCQEGHDDAEKGGGGEGGGGGKCVPVGGYPDELVLDVLND 247
            :|.|.|. ::..:|.|....|            :.:||||.|||.|.    ||       .|...
Zfish     7 SRRHGGKRESRSSGESRSSGG------------SAEGGGGGGGGSGS----GG-------GVEGP 48

  Fly   248 DLIAQVRNKLNSGGKDIFAQCVNAVKAFLAGEPFREFESSMYFHRYLQWKWLEAQPITYKTFRMY 312
            .|:..|:..|....:|...:..|         |.:...|..:|.|                   .
Zfish    49 TLLVDVKEFLAKAKEDFLKKWEN---------PAQNTASLDHFER-------------------L 85

  Fly   313 RVLGKGGFGEVCACQVRATGKMYACKKLEKKRIKKRKGESMVLIEKQILQKINSPFVVNLAYAYE 377
            :.||.|.||.|...:.:.:|:.:|.|.|:|:::.|.|.....|.||:|||.::.||:|.|.::::
Zfish    86 KTLGTGSFGRVMLVKHKESGQHFAMKILDKQKVVKLKQIEHTLNEKRILQAVSFPFLVRLEHSFK 150

  Fly   378 TKDALCLVLTIMNGGDLKFHIYNMG--GEPGFELERARFYAAEVACGLQHLHKQGIVYRDCKPEN 440
            ....|.:|:..:.||::..|:..:|  .||     .||||||::....::||...::|||.||||
Zfish   151 DNTNLYMVMEYVPGGEMFSHLRRIGRFSEP-----HARFYAAQIVLTFEYLHSLDLIYRDLKPEN 210

  Fly   441 ILLDDHGHVRISDLGLAVEIPEGEMVRGRV----GTVGYMAPEVIDNEKYAFSPDWFSFGCLLYE 501
            :|:|..|:::::|.|.|      :.|:||.    ||..|:|||:|.::.|..:.||::.|.|:||
Zfish   211 LLIDQQGYIQVTDFGFA------KRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYE 269

  Fly   502 MIEGQAPFRMRKEKVKREEVDRRVKEDPEKYSSKFNDEAKSMCQQLLAKSIKQRLGCRNGRMGGQ 566
            |..|..|| ...:.:   ::..::.....::.|.|:.:.|.:.:.||...:.:|.|  |.:.|..
Zfish   270 MAAGYPPF-FADQPI---QIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFG--NLKNGVN 328

  Fly   567 DVMAHPFFHSTQLNWRRLEAGMLEPPFVPDPHAVYAKDVLDIEQFSTVKGVNIDESDTNFYTKFN 631
            |:..|.:|.:|  :|..:....:|.||:|                 ..||    ..||:.:..::
Zfish   329 DIKGHKWFATT--DWIAIYQKKVEAPFIP-----------------KCKG----PGDTSNFDDYD 370

  Fly   632 TGSVSISWQNEMMETECFRELNVF 655
            ...:.:|     :..:|.:|...|
Zfish   371 EEEIRVS-----ITEKCGKEFAEF 389

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Gprk2NP_001263143.1 RGS 35..>111 CDD:295367
RGS <248..305 CDD:295367 9/56 (16%)
STKc_GRK4_like 308..597 CDD:270756 91/294 (31%)
S_TKc 309..574 CDD:214567 84/270 (31%)
prkacaaXP_021326630.1 STKc_PKA 80..369 CDD:271111 97/347 (28%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
10.910

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