DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Gprk2 and sgk2b

DIOPT Version :9

Sequence 1:	NP_001263143.1	Gene:	Gprk2 / 49045	FlyBaseID:	FBgn0261988	Length:	714	Species:	Drosophila melanogaster
Sequence 2:	XP_009290615.1	Gene:	sgk2b / 559050	ZFINID:	ZDB-GENE-060929-44	Length:	409	Species:	Danio rerio

Alignment Length:	294	Identity:	115/294 - (39%)
Similarity:	164/294 - (55%)	Gaps:	24/294 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly   309 FRMYRVLGKGGFGEVCACQVRATGKMYACKKLEKKRIKKRKGESMVLIEKQILQK-INSPFVVNL 372
            |...:|:|.|.||:|.....|..||.||.|.|:|..|..||.|..|:.|.::|.| :|.||:|.|
Zfish    82 FDYLKVIGTGSFGKVFLATHRENGKYYAVKVLQKHIILTRKEERNVMCEHRVLLKTLNHPFLVKL 146

  Fly   373 AYAYETKDALCLVLTIMNGGDLKFHIYNMG--GEPGFELERARFYAAEVACGLQHLHKQGIVYRD 435
            .::::||:.|.|||....||:|.:|:...|  ||     .||||||||:||.|.:||...|||||
Zfish   147 HFSFQTKERLYLVLDYACGGELFYHLQREGVFGE-----ARARFYAAEMACALGYLHSLKIVYRD 206

  Fly   436 CKPENILLDDHGHVRISDLGLAVEIPEGEMVRGRV----GTVGYMAPEVIDNEKYAFSPDWFSFG 496
            .||||||||..|||.::|.||.   .||...||..    ||..|:||||:..|:|..:.||:..|
Zfish   207 LKPENILLDSAGHVVLTDFGLC---KEGMSGRGTTRTFCGTPEYLAPEVLLQEEYDRTVDWWGLG 268

  Fly   497 CLLYEMIEGQAPFRMRKEKVKREEVDRRVKEDPEKYSSKFNDEAKSMCQQLLAKSIKQRLGCRNG 561
            .:|:||:.|..||    ....|.|:.|.:...|....:..:..|:.:.::||.:...:|||.:..
Zfish   269 AVLHEMLYGLPPF----YNADRLEMLRNIIYQPLALKAGVSSAARDLLKRLLNRDRAKRLGAKRD 329

  Fly   562 RMGGQDVMAHPFFHSTQLNWRRLEAGMLEPPFVP 595
            .:   ::.:|.||  :.:.|..|.|..::||:||
Zfish   330 LI---ELQSHAFF--SPIQWDELVAKKIQPPYVP 358

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Gprk2	NP_001263143.1	RGS	35..>111	CDD:295367
		RGS	<248..305	CDD:295367
		STKc_GRK4_like	308..597	CDD:270756	115/294 (39%)
		S_TKc	309..574	CDD:214567	106/271 (39%)
sgk2b	XP_009290615.1	S_TKc	82..339	CDD:214567	106/271 (39%)
sgk2b	XP_009290615.1	PKc_like	86..398	CDD:304357	114/290 (39%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910