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Protein Alignment Gprk2 and Akt2

DIOPT Version :9

Sequence 1:	NP_001263143.1	Gene:	Gprk2 / 49045	FlyBaseID:	FBgn0261988	Length:	714	Species:	Drosophila melanogaster
Sequence 2:	NP_001103678.1	Gene:	Akt2 / 11652	MGIID:	104874	Length:	481	Species:	Mus musculus

Alignment Length:	451	Identity:	135/451 - (29%)
Similarity:	203/451 - (45%)	Gaps:	99/451 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   199 HQDDGDESVK----CQEGHDDAEKGGGGEGGGGGKCVPVGGYPDELVLDVLNDDLIAQVRNKLNS 259
            |.|..||..:    .|...:..::.|.||.....||    |.|.:                   |
Mouse    89 HVDSPDEREEWMRAIQMVANSLKQRGPGEDAMDYKC----GSPSD-------------------S 130

  Fly   260 GGKDIFAQCVNAVKAFLAGEPFREFESSMYFHRYLQWKWLEAQPITYKTFRMYRVLGKGGFGEVC 324
            ...::....||..:|                            .:|...|...::||||.||:|.
Mouse   131 STSEMMEVAVNKARA----------------------------KVTMNDFDYLKLLGKGTFGKVI 167

  Fly   325 ACQVRATGKMYACKKLEKKRIKKRKGESMVLIEKQILQKINSPFVVNLAYAYETKDALCLVLTIM 389
            ..:.:|||:.||.|.|.|:.|..:...:..:.|.::||....||:..|.||::|.|.||.|:...
Mouse   168 LVREKATGRYYAMKILRKEVIIAKDEVAHTVTESRVLQNTRHPFLTALKYAFQTHDRLCFVMEYA 232

  Fly   390 NGGDLKFHIYNMGGEPGFELERARFYAAEVACGLQHLHKQGIVYRDCKPENILLDDHGHVRISDL 454
            |||:|.||   :..|..|..:|||||.||:...|::||.:.:||||.|.||::||..||::|:|.
Mouse   233 NGGELFFH---LSRERVFTEDRARFYGAEIVSALEYLHSRDVVYRDIKLENLMLDKDGHIKITDF 294

  Fly   455 GLAVE-IPEGEMVRGRVGTVGYMAPEVIDNEKYAFSPDWFSFGCLLYEMIEGQAPFRMRK----- 513
            ||..| |.:|..::...||..|:||||:::..|..:.||:..|.::|||:.|:.||..:.
Mouse   295 GLCKEGISDGATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHERLF 359

  Fly   514 EKVKREEVDRRVKEDPEKYSSKFNDEAKSMCQQLLAKSIKQRLGCRNGRMGGQDVMAHPFFHSTQ 578
            |.:..||:         ::......||||:...||.|..|||||  .|....::||.|.||.|
Mouse   360 ELILMEEI---------RFPRTLGPEAKSLLAGLLKKDPKQRLG--GGPSDAKEVMEHRFFLS-- 411

  Fly   579 LNWRRLEAGMLEPPFVPDPHAVYAKDVLDIEQFSTVKGVNIDESDTNFY-TKFNTGSVSIS 638
            :||:.:....|.|||.|..                     ..|.||.:: .:|...|::|:
Mouse   412 INWQDVVQKKLLPPFKPQV---------------------TSEVDTRYFDDEFTAQSITIT 451

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.