Protein Alignment Gprk2 and grk1

DIOPT Version :9

• Sequence 1: NP_001263143.1
• Gene: Gprk2 / 49045
• FlyBaseID: FBgn0261988
• Length: 714
• Species: Drosophila melanogaster
• Sequence 2: XP_002937018.3
• Gene: grk1 / 100486335
• XenbaseID: XB-GENE-1012638
• Length: 559
• Species: Xenopus tropicalis
• Alignment Length: 657
• Identity: 251/657 - (38%)
• Similarity: 362/657 - (55%)
• Gaps: 136/657 - (20%)

  Fly     3 LENIVANTVYLKAR---EGGSDSNKGKSKKWRKILQFPHISQCINLKDKLDISYGYVIDQQPIGR 64
            ||.:|||:.|:.||   :||.:....::||:|..|:.|.:|:|.:||||||:.:..:..:||||:
 Frog     6 LETVVANSAYITARGSFDGGFNPQITRNKKYRARLKLPPLSECEHLKDKLDLQFENICVKQPIGK 70

  Fly    65 ELFRLFCENKRPVYFRYITFLDEVVKYEIEYISNRIFIGHDIGRRFLDVEAQLELRNGSGGDALD 129
            :||:.|.|:..  :...:...:::..|::....:|::....|..::||.:::
 Frog    71 KLFQEFLESAE--FTHIVEIWNDIEDYDVAEDEDRLYKARGIINKYLDSDSK------------- 120

  Fly   130 AETQEELLLNSSNANPTETAETEHCNNTTANNCNNINNSNNSQHSSDINHKKLDTRNHNGDDATG 194
                                  :.|:
 Frog   121 ----------------------QFCH--------------------------------------- 124

  Fly   195 NGSSHQDDGDESVKCQEGHDDAEKGGGGEGGGGGKCVPVGGYPDE-LVLDVLNDDLIAQVRNKLN 258
                                                     |.|| .::.|:.|         .|
 Frog   125 -----------------------------------------YLDEKAIIKVVQD---------CN 139

  Fly   259 SGGKDIFAQCVNAVKAFLAGEPFREFESSMYFHRYLQWKWLEAQPITYKTFRMYRVLGKGGFGEV 323
            .....:|.|...:...:|....|.:::.|.||.::||||.||||||....|..:|:|||||||||
 Frog   140 KVSNMLFKQLHKSTLDYLKENAFAQYKESKYFSKFLQWKKLEAQPIGDDWFMDFRILGKGGFGEV 204

  Fly   324 CACQVRATGKMYACKKLEKKRIKKRKGESMVLIEKQILQKINSPFVVNLAYAYETKDALCLVLTI 388
            .|.|:||||||||||||.|||:|||||....::||:||.|::|.|:|:||||::||:.:|||:||
 Frog   205 SATQMRATGKMYACKKLSKKRLKKRKGFEGAMVEKRILAKVHSRFIVSLAYAFQTKNDVCLVMTI 269

  Fly   389 MNGGDLKFHIYNMGGE-PGFELERARFYAAEVACGLQHLHKQGIVYRDCKPENILLDDHGHVRIS 452
            ||||||:||||||..| ||.:..||.||.|::..||:|||:..|:|||.||||:|||:.|:||||
 Frog   270 MNGGDLRFHIYNMDEENPGIDEHRASFYTAQIISGLEHLHQNRIIYRDLKPENVLLDNDGNVRIS 334

  Fly   453 DLGLAVEIPEGE-MVRGRVGTVGYMAPEVIDNEKYAFSPDWFSFGCLLYEMIEGQAPFRMRKEKV 516
            |||||||:.|.: ..:|..||.|:||||::..|:|.::.|:||.|..|||||..:.|||.|.|||
 Frog   335 DLGLAVELKEKKSKAKGYAGTPGFMAPELLQGEEYDYAVDYFSLGVTLYEMIAARGPFRCRGEKV 399

  Fly   517 KREEVDRRVKEDPEKYSSKFNDEAKSMCQQLLAKSIKQRLGCRNGRMGGQDVMAHPFFHSTQLNW 581
            :.:|:..|:..|...||.||:.:.||:|:.||.|..|:|:|.:||..  .::..|.||..  :||
 Frog   400 ENKELKNRILNDSVTYSGKFSLDCKSICEALLDKDPKKRMGFKNGNC--NEIRVHLFFRG--INW 460

  Fly   582 RRLEAGMLEPPFVPDPHAVYAKDVLDIEQFSTVKGVNIDESDTNFYTKFNTGSVSISWQNEMMET 646
            |:||||:|.|||.||...|||||:.|:..|||||||.:||||...:.:|.:|::||.||.||:||
 Frog   461 RKLEAGILPPPFAPDSRIVYAKDIQDVGAFSTVKGVTLDESDNKLFDEFASGNISIPWQEEMVET 525

  Fly   647 ECFRELN 653
            ..|.|:|
 Frog   526 GIFDEIN 532

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gprk2	NP_001263143.1	RGS	35..>111	CDD:295367	20/75 (27%)
		RGS	<248..305	CDD:295367	17/56 (30%)
		STKc_GRK4_like	308..597	CDD:270756	160/290 (55%)
		S_TKc	309..574	CDD:214567	146/266 (55%)
grk1	XP_002937018.3	RGS_GRK1	43..178	CDD:188702	38/260 (15%)
		STKc_GRK1	188..475	CDD:270759	159/290 (55%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1104340at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24355
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.020