Protein Alignment Gprk2 and grk3

DIOPT Version :9

• Sequence 1: NP_001263143.1
• Gene: Gprk2 / 49045
• FlyBaseID: FBgn0261988
• Length: 714
• Species: Drosophila melanogaster
• Sequence 2: XP_002932117.2
• Gene: grk3 / 100379889
• XenbaseID: XB-GENE-6043587
• Length: 688
• Species: Xenopus tropicalis
• Alignment Length: 654
• Identity: 201/654 - (30%)
• Similarity: 299/654 - (45%)
• Gaps: 141/654 - (21%)

  Fly     2 ELENIVANTVYLKAREGGSDSNKGKSKKWRKILQFPHISQCIN--LKDKLDISYGYVIDQQPIGR 64
            :||.::|:..||.|.|....:...::.| :.:|..|.|...:.  |:::.::::..:.:|: ||.
 Frog     3 DLEAVLADVSYLMAMEKSKSTPAARASK-KIVLPEPSIRSVMQKYLEERGELTFDKIFNQK-IGF 65

  Fly    65 ELFRLFCENKRPVYFRYITFLDEVVKYEIEYISNRIFIGHDIGRRFLDVEAQLELRNGSGGDALD 129
            .||:.||.|........:.|.:|:.:||                 .||.|   |.|........|
 Frog    66 LLFKDFCMNDMDEGVPQLKFYEEIKEYE-----------------KLDSE---EDRLCRSRQIYD 110

  Fly   130 AETQEELLLNSSNANPTETAETEHCNNTTANNCNNINNSNNSQHSSDINHKKLDTRNHNGDDATG 194
            ....:|||   |.::|......:|.....|.
 Frog   111 TYIMKELL---SCSHPFSKQAVDHVQAHLAK---------------------------------- 138

  Fly   195 NGSSHQDDGDESVKCQEGHDDAEKGGGGEGGGGGKCVPVGGYPDELVLDVLNDDLIAQVRNKLNS 259
                                              |.||
 Frog   139 ----------------------------------KQVP--------------------------- 142

  Fly   260 GGKDIFAQCVNAVKAFLAGEPFREFESSMYFHRYLQWKWLEAQ-PITYKTFRMYRVLGKGGFGEV 323
              ..:|...:..:...|.|:.|:.|..|..|.|:.|||.:|.. .:|...|.::|::|:||||||
 Frog   143 --PTLFQPYIEEICDSLRGKIFQRFIESDRFTRFCQWKNVELNIHLTMNDFSVHRIIGRGGFGEV 205

  Fly   324 CACQVRATGKMYACKKLEKKRIKKRKGESMVLIEKQILQKINS---PFVVNLAYAYETKDALCLV 385
            ..|:...||||||.|.|:|||||.::||::.|.|:.:|..:::   ||:|.:.||:.|.|.||.:
 Frog   206 YGCRKADTGKMYAMKCLDKKRIKMKQGETLALNERIMLSLVSTGDCPFIVCMTYAFHTPDKLCFI 270

  Fly   386 LTIMNGGDLKFHIYNMGGEPGFELERARFYAAEVACGLQHLHKQGIVYRDCKPENILLDDHGHVR 450
            |.:||||||.:|:...|   .|..:..||||||:..||:|:|.:.:||||.||.|||||:|||||
 Frog   271 LDLMNGGDLHYHLSQHG---VFSEKEMRFYAAEIILGLEHMHHRFVVYRDLKPANILLDEHGHVR 332

  Fly   451 ISDLGLAVEIPEGEMVRGRVGTVGYMAPEVID-NEKYAFSPDWFSFGCLLYEMIEGQAPFRMRKE 514
            |||||||.:..: :.....|||.|||||||:. ...|..|.||||.||:|::::.|.:|||..|.
 Frog   333 ISDLGLACDFSK-KKPHASVGTHGYMAPEVLQKGTAYDSSADWFSLGCMLFKLLRGHSPFRQHKT 396

  Fly   515 KVKREEVDRRVKEDPEKYSSKFNDEAKSMCQQLLAKSIKQRLGCRNGRMGGQDVMAHPFFHSTQL 579
            |.| .|:||.......:....|:.|.||:.:.||.:.:.:||||:.|  |.|:|..|.||..  :
 Frog   397 KDK-HEIDRMTLTMNVELPDSFSPELKSLLEGLLQRDVSKRLGCQGG--GAQEVKEHAFFKG--I 456

  Fly   580 NWRRLEAGMLEPPFVPDPHAVYAKDVLDIEQF--STVKGVNIDESDTNFYTKFNTGSVSISWQNE 642
            :|:::......||.:|....|.|.|..||..|  ...||:.:.:||...|..|.. .:|..||.|
 Frog   457 DWQQVYLQKYPPPLIPPRGEVNAADAFDIGSFDEEDTKGIKLLDSDQELYKNFPL-VISERWQQE 520

  Fly   643 MMET 646
            :.||
 Frog   521 VAET 524

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gprk2	NP_001263143.1	RGS	35..>111	CDD:295367	15/77 (19%)
		RGS	<248..305	CDD:295367	12/57 (21%)
		STKc_GRK4_like	308..597	CDD:270756	130/292 (45%)
		S_TKc	309..574	CDD:214567	124/268 (46%)
grk3	XP_002932117.2	RGS_GRK2_GRK3	30..186	CDD:188701	45/277 (16%)
		STKc_GRK3	185..530	CDD:270781	149/350 (43%)
		PH_GRK2_subgroup	553..670	CDD:269946

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1104340at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010