| Sequence 1: | NP_001353453.1 | Gene: | ATP2B1 / 490 | HGNCID: | 814 | Length: | 1249 | Species: | Homo sapiens |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_001014689.3 | Gene: | PMCA / 43787 | FlyBaseID: | FBgn0259214 | Length: | 1255 | Species: | Drosophila melanogaster |
| Alignment Length: | 1292 | Identity: | 751/1292 - (58%) |
|---|---|---|---|
| Similarity: | 906/1292 - (70%) | Gaps: | 134/1292 - (10%) |
- Green bases have known domain annotations that are detailed below.
|
Human 21 ANHDG---DFGITLAELRALMELRSTDALRKIQESYGDVYGICTKLKTSPNEGLSGNPADLERRE 82
Human 83 AVFGKNFIPPKKPKTFLQLVWEALQDVTLIILEIAAIVSLGLSFYQPPEGDNALCGEVSVGEEEG 147
Human 148 EGETGWIEGAAILLSVVCVVLVTAFNDWSKEKQFRGLQSRIEQEQKFTVIRGGQVIQIPVADITV 212
Human 213 GDIAQVKYGDLLPADGILIQGNDLKIDESSLTGESDHVKKSLDKDPLLLSGTHVMEGSGRMVVTA 277
Human 278 VGVNSQTGIIFTLLGAGGEEEE---KKDEKKKEKKNKKQDGAIENRNKAKAQDGAA------MEM 333
Human 334 QPLKSEEGGDGDEKDKKKANLP------------KKEKSVLQGKLTKLAVQIGKAGLLMSAITVI 386
Human 387 ILVLYFVIDTFWVQKRPWLAECTPIYIQYFVKFFIIGVTVLVVAVPEGLPLAVTISLAYSVKKMM 451
Human 452 KDNNLVRHLDACETMGNATAICSDKTGTLTMNRMTVVQAYINEKHYKKVPEPEAIPPNILSYLVT 516
Human 517 GISVNCAYTSKILPPEKEGGLPRHVGNKTECALLGLLLDLKRDYQDVRNEIPEEALYKVYTFNSV 581
Human 582 RKSMSTVLKNSDGSYRIFSKGASEIILKKCFKILSANGEAKVFRPRDRDDIVKTVIEPMASEGLR 646
Human 647 TICLAFRDFPAG---------EPEPEWDNENDIVTGLTCIAVVGIEDPVRPEVPDAIKKCQRAGI 702
Human 703 TVRMVTGDNINTARAIATKCGILHPGEDFLCLEGKDFNRRIRNEKGEIEQERIDKIWPKLRVLAR 767
Human 768 SSPTDKHTLVKGIIDSTVSDQRQVVAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTD 832
Human 833 DNFTSIVKAVMWGRNVYDSISKFLQFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTL 897
Human 898 ASLALATEPPTESLLLRKPYGRNKPLISRTMMKNILGHAFYQLVVVFTLLFAGEKFFDIDSGRNA 962
Human 963 PLHAPPSEHYTIVFNTFVLMQLFNEINARKIHGERNVFEGIFNNAIFCTIVLGTFVVQIIIVQFG 1027
Human 1028 GKPFSCSELSIEQWLWSIFLGMGTLLWGQLISTIPTSRLKFLKEAGHGTQKEEIPEEELAED-VE 1091
Human 1092 EIDHAERELRRGQILWFRGLNRIQTQMDVVNAFQSGSSIQGALRRQPSIASQHHDIRVVNAFRSS 1156
Human 1157 LYEGLEKPESRSSIHNFMT------------HPEFRI-----------EDSEPHIP--------- 1189
Human 1190 --LIDDTDAEDDAP-----------TKRNSSPP---PSPNKNNNAVDSGIHLTIEMN 1230 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| ATP2B1 | NP_001353453.1 | ATPase-IIB_Ca | 15..1064 | CDD:273668 | 700/1075 (65%) |
| ATP_Ca_trans_C | 1103..1178 | CDD:403580 | 25/86 (29%) | ||
| PMCA | NP_001014689.3 | ATPase-IIB_Ca | 1..1057 | CDD:273668 | 700/1075 (65%) |
| Cation_ATPase_N | 36..104 | CDD:279080 | 46/68 (68%) | ||
| E1-E2_ATPase | 172..448 | CDD:278548 | 173/288 (60%) | ||
| Cation_ATPase | 505..598 | CDD:289987 | 53/92 (58%) | ||
| HAD_like | 676..807 | CDD:119389 | 110/130 (85%) | ||
| Cation_ATPase_C | 873..1051 | CDD:279079 | 120/177 (68%) | ||
| ATP_Ca_trans_C | 1096..1142 | CDD:289209 | 24/75 (32%) |
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 1 | 1.000 | 256 | 1.000 | Domainoid score | I2040 |
| eggNOG | 1 | 0.900 | - | - | E2759_KOG0204 | |
| Hieranoid | 1 | 1.000 | - | - | ||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 1 | 1.050 | 1374 | 1.000 | Inparanoid score | I126 |
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 1 | 1.010 | - | - | QHG53587 | |
| OrthoDB | 1 | 1.010 | - | - | D115892at2759 | |
| OrthoFinder | 1 | 1.000 | - | - | FOG0000362 | |
| OrthoInspector | 1 | 1.000 | - | - | otm40424 | |
| orthoMCL | 1 | 0.900 | - | - | OOG6_100143 | |
| Panther | 1 | 1.100 | - | - | O | PTHR24093 |
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 1 | 1.030 | - | avgDist | Average_Evolutionary_Distance | R99 |
| SonicParanoid | 1 | 1.000 | - | - | X220 | |
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 1 | 0.960 | - | - | ||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 14 | 13.870 | |||||