DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ACR and CG10041

DIOPT Version :9

Sequence 1:	NP_001088.2	Gene:	ACR / 49	HGNCID:	126	Length:	421	Species:	Homo sapiens
Sequence 2:	NP_650177.2	Gene:	CG10041 / 41496	FlyBaseID:	FBgn0038014	Length:	287	Species:	Drosophila melanogaster

Alignment Length:	253	Identity:	71/253 - (28%)
Similarity:	115/253 - (45%)	Gaps:	39/253 - (15%)

- Green bases have known domain annotations that are detailed below.

Human    54 WPWMVSLQIFTYNSHRY--HTCGGSLLNSRWVLTAAHCFVGKNNVHDWRLVFGAKEITYGNNKPV 116
            :|::||:   ..|...|  |.|.|.:|::.:||:|||| :..|......:..||..:   |::.
  Fly    50 YPYIVSI---GENLKGYYKHLCVGVILSNEFVLSAAHC-IQTNPTKQLYVAGGADSL---NSRK- 106

Human   117 KAPLQERYVEKIIIHEKYN---SATEGNDIALVEITP--PISCGRFIGPGCLPHFKAGLPR---G 173
                |.|:   .::..:::   ....|||||::.|.|  |:...||.....     ||.|:   |
  Fly   107 ----QTRF---FVVERRWHPQFRVLGGNDIAVLRIYPKFPLDDVRFRSINF-----AGKPQRDSG 159

Human   174 SQSCWVAGWGYIEEKAPRPSSILMEARVDLIDLDLCNSTQWYNGRVQPTNVCAGYPVGKIDTCQG 238
            :|:..| |||.:.....|.   |.|.....::.|.|..:..: ..::|.::||.:..|....|.|
  Fly   160 TQASLV-GWGRVGVGKIRK---LQEMPFLTMENDECQQSHRF-VFLKPLDICAMHLKGPRGPCDG 219

Human   239 DSGGPLMCKDSKESAYVVVGITSWGVGCARAKRPGIYTATWPYLNWIASKIGSNALRM 296
            |||.||| ..:||..|   |:.|:|.......:|..:|....|.:||...:.|.|.|:
  Fly   220 DSGAPLM-NVAKEKLY---GLLSYGRKACTPLKPYAFTRINAYSSWIQESMDSMAARL 273

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ACR	NP_001088.2	Tryp_SPc	42..285	CDD:214473	66/240 (28%)
		Tryp_SPc	43..288	CDD:238113	68/243 (28%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	297..316		71/253 (28%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	327..383
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	397..421
CG10041	NP_650177.2	Tryp_SPc	49..264	CDD:238113	68/242 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	0	0.000