DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment boca and Mesd

DIOPT Version :9

Sequence 1:	NP_724578.1	Gene:	boca / 48986	FlyBaseID:	FBgn0004132	Length:	180	Species:	Drosophila melanogaster
Sequence 2:	NP_001008346.1	Gene:	Mesd / 308796	RGDID:	1310344	Length:	224	Species:	Rattus norvegicus

Alignment Length:	177	Identity:	84/177 - (47%)
Similarity:	122/177 - (68%)	Gaps:	9/177 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 RLVLLLLALTPLVLAKKFK--------EEEKPAWAKKDIRDYSEADLERLLDQWEEDEEPLEDDE 60
            |.|||.|..:.|:|....:        |...|...|||||||::||:.|||:|||:|:: :|:.:
  Rat     8 RAVLLFLCASDLLLLSPPEAYATDTPGEAITPPRKKKDIRDYNDADMARLLEQWEKDDD-IEEGD 71

  Fly    61 LPEHLRPQPKLDLSNLDSKSPEDLLKVSKKGRTLMTFVSVTGNPTREESDTITKLWQTSLWNNHI 125
            ||||.||...:|.|.||...||.:||::|||:|||.||:::||||.:|::.||.|||.||:|.:.
  Rat    72 LPEHKRPSAPIDFSKLDPGKPESILKMTKKGKTLMMFVTISGNPTEKETEEITSLWQGSLFNANY 136

  Fly   126 QAERYMVDDNRAIFLFKDGTQAWDAKDFLIEQERCKGVTIENKEYPG 172
            ..:|::|..:||||:.:||:.||:.||||:.|:||..||:|.:.|||
  Rat   137 DVQRFIVGSDRAIFMLRDGSYAWEIKDFLVNQDRCAEVTLEGQMYPG 183

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
boca	NP_724578.1	Mesd	31..178	CDD:287194	75/142 (53%)
Mesd	NP_001008346.1	Chaperone domain. /evidence=ECO:0000250\|UniProtKB:Q9ERE7	1..155		67/147 (46%)
		Mesd	43..192	CDD:401992	75/142 (53%)
		Escort domain. /evidence=ECO:0000250\|UniProtKB:Q9ERE7	156..195		15/28 (54%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	178..224		3/6 (50%)
		Prevents secretion from ER	221..224
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166353899
Domainoid	1	1.000	172	1.000	Domainoid score	I3637
eggNOG	1	0.900	-	-		E1_KOG4357
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H11347
Inparanoid	1	1.050	174	1.000	Inparanoid score	I3982
OMA	1	1.010	-	-		QHG45813
OrthoDB	1	1.010	-	-		D1590303at2759
OrthoFinder	1	1.000	-	-		FOG0007230
OrthoInspector	1	1.000	-	-		oto98128
orthoMCL	1	0.900	-	-		OOG6_107397
Panther	1	1.100	-	-	LDO	PTHR17600
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X5334
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	16	15.770