DRSC/TRiP Functional Genomics Resources

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Protein Alignment Src64B and SLA2

DIOPT Version :9

Sequence 1:NP_001286937.1 Gene:Src64B / 48973 FlyBaseID:FBgn0262733 Length:553 Species:Drosophila melanogaster
Sequence 2:XP_016883587.1 Gene:SLA2 / 84174 HGNCID:17329 Length:288 Species:Homo sapiens


Alignment Length:213 Identity:72/213 - (33%)
Similarity:107/213 - (50%) Gaps:25/213 - (11%)


- Green bases have known domain annotations that are detailed below.


  Fly    55 GSLDSRYTPDPNHRGPLKIGGKGGVDIIRPRTTPTGVPGVVLKRVVVALYDYKSRDESDLSFMKG 119
            |||.||....|:......:.|:|.|.:...|:          |...|||..:.:...::||...|
Human     2 GSLPSRRKSLPSPSLSSSVQGQGPVTMEAERS----------KATAVALGSFPAGGPAELSLRLG 56

  Fly   120 DRMEVIDDTESDWWRVVNLTTRQEGLIPLNFVAEERSVNSEDWFFENVLRKEADKLLLAEENPRG 184
            :.:.::.: :.|||.|::..:.:|..||...||:.    |..|.:|.:.|::|::|||...||.|
Human    57 EPLTIVSE-DGDWWTVLSEVSGREYNIPSVHVAKV----SHGWLYEGLSREKAEELLLLPGNPGG 116

  Fly   185 TFLVRPSEHNPNGYSLSVK-----DWEDGRGYHVKHYRIKPLDNGGYYIATNQTFPSLQALVMAY 244
            .||:|.|:.....|||||:     .|:     .::||||..||||..||:...|||||||||..|
Human   117 AFLIRESQTRRGSYSLSVRLSRPASWD-----RIRHYRIHCLDNGWLYISPRLTFPSLQALVDHY 176

  Fly   245 SKENALGLCHILSRPCPK 262
            |.....||.:..:.|..|
Human   177 SDRQKSGLPYFHASPYAK 194

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Src64BNP_001286937.1 SH3_Src_like 99..150 CDD:212779 13/50 (26%)
SH2_Src_family 158..259 CDD:199827 44/105 (42%)
STYKc 285..537 CDD:214568
PTKc_Src_like 289..538 CDD:270630
SLA2XP_016883587.1 None
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

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