DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Src64B and ATN1

DIOPT Version :9

Sequence 1:	NP_001286937.1	Gene:	Src64B / 48973	FlyBaseID:	FBgn0262733	Length:	553	Species:	Drosophila melanogaster
Sequence 2:	NP_189393.1	Gene:	ATN1 / 822378	AraportID:	AT3G27560	Length:	356	Species:	Arabidopsis thaliana

Alignment Length:	296	Identity:	80/296 - (27%)
Similarity:	134/296 - (45%)	Gaps:	30/296 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly   273 ELRDKYEIPRSEIQLLRKLGRGNFGEVFYGKWRNSIDVAVKTLREG------TMSTAAFLQEAAI 331
            ||..|:.:....:.:..|:|.|...:|:.||:||. .||:|.::.|      ......|.:|.|:
plant    14 ELDPKWLVDPRHLFVGPKIGEGAHAKVYEGKYRNQ-TVAIKIIKRGESPEEIAKRDNRFAREIAM 77

  Fly   332 MKKFRHNRLVALYAVCSQEEPIYIVQEYMSKGSLLDFLREGDGRYLHFEDLIYIATQVASGMEYL 396
            :.|.:|..||.....| :|..:.||.|.:..|:|..:|.....:.|.....:..|..:|..||.|
plant    78 LSKVQHKNLVKFIGAC-KEPMMVIVTELLLGGTLRKYLVSLRPKRLDIRLAVGFALDIARAMECL 141

  Fly   397 ESKQLIHRDLAARN-VLIGENNVAKICDFGLARVIADDEYCPKQGSRFPVKWTAPEAIIYGKFSI 460
            .|..:|||||...| :|..::...|:.||||||..:..|....:...:  :|.|||  :|...::
plant   142 HSHGIIHRDLKPENLILSADHKTVKLADFGLAREESLTEMMTAETGTY--RWMAPE--LYSTVTL 202

  Fly   461 ----------KSDVWSYGILLMELFTYGQVPYPGMHSREVIENIERGFRMPKPTNHYFPDNIYQL 515
                      |.|.:|:.|:|.||. ..::|:.||.:.:..  ....|:..:|:....|.::..:
plant   203 RQGEKKHYNHKVDAYSFAIVLWELI-LNKLPFEGMSNLQAA--YAAAFKNLRPSAEDLPGDLEMI 264

  Fly   516 LLQCWDAVPEKRPTF----EFLNHYFESFSVTSEVP 547
            :..||...|.:||.|    :.|..|..:.|....:|
plant   265 VTSCWKEDPNERPNFTEIIQMLLRYLTTVSAPQIIP 300

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Src64B	NP_001286937.1	SH3_Src_like	99..150	CDD:212779
		SH2_Src_family	158..259	CDD:199827
		STYKc	285..537	CDD:214568	74/272 (27%)
		PTKc_Src_like	289..538	CDD:270630	75/269 (28%)
ATN1	NP_189393.1	STKc_MAP3K-like	32..286	CDD:270901	72/262 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	148	1.000	Inparanoid score	I1725
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X88
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.960