DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Src64B and STY8

DIOPT Version :9

Sequence 1:	NP_001286937.1	Gene:	Src64B / 48973	FlyBaseID:	FBgn0262733	Length:	553	Species:	Drosophila melanogaster
Sequence 2:	NP_179361.1	Gene:	STY8 / 816278	AraportID:	AT2G17700	Length:	546	Species:	Arabidopsis thaliana

Alignment Length:	326	Identity:	99/326 - (30%)
Similarity:	169/326 - (51%)	Gaps:	39/326 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly   236 SLQALVM-AYSKENALGLCHILSR--------PCPKPQ---------------PQMWDLGPELRD 276
            ||...|: .:|:|...||...||:        |..|.:               |...::..:..|
plant   213 SLDVFVVDGWSQEETDGLRDALSKEILKLKDQPGSKQKSISFFEHDKSSNELIPACIEIPTDGTD 277

  Fly   277 KYEIPRSEIQLLRKLGRGNFGEVFYGKWRNSIDVAVKTLREGTMST---AAFLQEAAIMKKFRHN 338
            ::||..:::::.:|:..|::|::..|.: .|.:||:|.|:...::.   ..|.||..||:|.||.
plant   278 EWEIDVTQLKIEKKVASGSYGDLHRGTY-CSQEVAIKFLKPDRVNNEMLREFSQEVFIMRKVRHK 341

  Fly   339 RLVALYAVCSQEEPIYIVQEYMSKGSLLDFLREGDGRYLHFEDLIYIATQVASGMEYLESKQLIH 403
            .:|.....|::...:.||.|:|::||:.|||.:....: ..:.|:.:|..||.||.||....:||
plant   342 NVVQFLGACTRSPTLCIVTEFMARGSIYDFLHKQKCAF-KLQTLLKVALDVAKGMSYLHQNNIIH 405

  Fly   404 RDLAARNVLIGENNVAKICDFGLARVIADDEYCPKQGSRFPVKWTAPEAIIYGKFSIKSDVWSYG 468
            |||...|:|:.|:.:.|:.|||:|||..:......:...:  :|.|||.|.:..::.|:||:||.
plant   406 RDLKTANLLMDEHGLVKVADFGVARVQIESGVMTAETGTY--RWMAPEVIEHKPYNHKADVFSYA 468

  Fly   469 ILLMELFTYGQVPYPGMHS-REVIENIERGFR--MPKPTNHYFPDNIYQLLLQCWDAVPEKRPTF 530
            |:|.||.| |.:||..:.. :..:..:::|.|  :||.|:    ..:..||.:||...||:||.|
plant   469 IVLWELLT-GDIPYAFLTPLQAAVGVVQKGLRPKIPKKTH----PKVKGLLERCWHQDPEQRPLF 528

  Fly   531 E 531
            |
plant   529 E 529

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Src64B	NP_001286937.1	SH3_Src_like	99..150	CDD:212779
		SH2_Src_family	158..259	CDD:199827	9/31 (29%)
		STYKc	285..537	CDD:214568	84/253 (33%)
		PTKc_Src_like	289..538	CDD:270630	84/249 (34%)
STY8	NP_179361.1	ACT_TyrKc	172..239	CDD:153200	9/25 (36%)
		Pkinase_Tyr	286..535	CDD:285015	84/253 (33%)
		STKc_MAP3K-like	292..535	CDD:270901	83/247 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	165	1.000	Domainoid score	I1208
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000006
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X88
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.910