DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Src64B and Grap

DIOPT Version :9

Sequence 1:	NP_001286937.1	Gene:	Src64B / 48973	FlyBaseID:	FBgn0262733	Length:	553	Species:	Drosophila melanogaster
Sequence 2:	NP_082093.1	Gene:	Grap / 71520	MGIID:	1918770	Length:	217	Species:	Mus musculus

Alignment Length:	169	Identity:	47/169 - (27%)
Similarity:	88/169 - (52%)	Gaps:	21/169 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly   101 VALYDYKSRDESDLSFMKGDRMEVID-DTESDWWRVVNLTTRQEGLIPLNFVAEERSVNSEDWFF 164
            ||||.:::.:..:|:|.|||.::::: :.:.:|::..  ....||.:|.|::    .|....|:.
Mouse     4 VALYSFQATESDELAFNKGDTLKILNMEDDQNWYKAE--LRGAEGFVPKNYI----RVKPHPWYS 62

  Fly   165 ENVLRKEADKLLLAEENPRGTFLVRPSEHNPNGYSLSVKDWEDGRGYHVKHYRIKPLDNGGYYIA 229
            ..:.|:.|::.|: :.|..|.||:|.||.:|..:|:||     ..|..|:|:::....:|.|::
Mouse    63 GRISRQLAEETLM-KRNHLGAFLIRESESSPGEFSVSV-----NYGDQVQHFKVLREASGKYFL- 120

  Fly   230 TNQTFPSLQALVMAY-----SKENALGLCHILSRPCPKP 263
            ..:.|.||..||..|     :|...:.||.  .:|..||
Mouse   121 WEEKFNSLNELVDFYRTTTIAKRRQIFLCD--EQPLIKP 157

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Src64B	NP_001286937.1	SH3_Src_like	99..150	CDD:212779	13/49 (27%)
		SH2_Src_family	158..259	CDD:199827	29/105 (28%)
		STYKc	285..537	CDD:214568
		PTKc_Src_like	289..538	CDD:270630
Grap	NP_082093.1	SH3_GRAP_N	2..55	CDD:212881	14/56 (25%)
		SH2_Grb2_like	56..150	CDD:199828	28/100 (28%)
		SH3	162..214	CDD:302595
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000006
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910