Protein Alignment Src64B and fynb

DIOPT Version :10

• Sequence 1: NP_001286937.1
• Gene: Src64B / 48973
• FlyBaseID: FBgn0262733
• Length: 553
• Species: Drosophila melanogaster
• Sequence 2: XP_068071652.2
• Gene: fynb / 574422
• ZFINID: ZDB-GENE-050706-89
• Length: 596
• Species: Danio rerio
• Alignment Length: 613
• Identity: 264/613 - (43%)
• Similarity: 365/613 - (59%)
• Gaps: 86/613 - (14%)

  Fly     1 MGNKCCSKRQ------DQELALAYPTGGYKKSDYTFGQTHINSSGGGNMGGVLGQKHN-NGGSLD 58
            ||...|..::      |::.:|:....||:.......|.:...||.|.....:...:| :|.::.
Zfish     1 MGCVQCKDKEAAKLTDDRDTSLSQSGVGYRYGVDPTPQHYPAFSGTGTAVAAIPNYNNFHGAAVP 65

  Fly    59 SRYT-----PDPNHRGPLKIGGKGGVDIIRPRTTPTGVPGVVLKRVVVALYDYKSRDESDLSFMK 118
            ...|     ....|:|.|:..|..||.:.                  ||||||::|.|.||||.|
Zfish    66 QGMTVFGGISTSTHQGTLRTRGGTGVTLF------------------VALYDYEARTEDDLSFRK 112

  Fly   119 GDRMEVIDDTESDWWRVVNLTTRQEGLIPLNFVAEERSVNSEDWFFENVLRKEADKLLLAEENPR 183
            |::.::|:.||.|||...:|||...|.||.|:||...|:.:|||:|..:.||:|::.||:..|||
Zfish   113 GEKFQIINSTEGDWWDARSLTTGGTGYIPSNYVAPVDSIQAEDWYFGKLGRKDAERQLLSTGNPR 177

  Fly   184 GTFLVRPSEHNPNGYSLSVKDWEDGRGYHVKHYRIKPLDNGGYYIATNQTFPSLQALVMAYSKEN 248
            ||||:|.||.....:|||::||:|.:|.|||||:|:.||:|||||.|...|.:||.||..|: |.
Zfish   178 GTFLIRESETTKGAFSLSIRDWDDVKGDHVKHYKIRKLDSGGYYITTRAQFETLQQLVQHYT-ER 241

  Fly   249 ALGLCHILSRPCPKPQPQMWDLGPELRDKYEIPRSEIQLLRKLGRGNFGE--------------- 298
            |.|||..|..||.|..|::.||..:.:|.:||||..:||:::||.|.|||
Zfish   242 AAGLCCRLVVPCHKGMPRLTDLSVKTKDVWEIPRESLQLIKRLGNGQFGEVWMESADGLCFNLTG 306

  Fly   299 -------------------------------------VFYGKWRNSIDVAVKTLREGTMSTAAFL 326
                                                 |:||.|..:..||:|||:.||||..:||
Zfish   307 VCMVYTPDTVGLSHDSWEIARESLTLDMKLGAGCFADVWYGTWNGNTKVAIKTLKPGTMSPESFL 371

  Fly   327 QEAAIMKKFRHNRLVALYAVCSQEEPIYIVQEYMSKGSLLDFLREGDGRYLHFEDLIYIATQVAS 391
            :||.||||.||::||.||||.| |||||||.|||.||||||||::|:||.|...:|:.:|.|||.
Zfish   372 EEAQIMKKLRHDKLVQLYAVVS-EEPIYIVTEYMGKGSLLDFLKDGEGRALKLPNLVDMAAQVAG 435

  Fly   392 GMEYLESKQLIHRDLAARNVLIGENNVAKICDFGLARVIADDEYCPKQGSRFPVKWTAPEAIIYG 456
            ||.|:|....|||||.:.|:|:|::.|.||.||||||:|.|:||..:||::||:|||||||.:||
Zfish   436 GMAYIERMNYIHRDLRSANILVGDSLVCKIADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYG 500

  Fly   457 KFSIKSDVWSYGILLMELFTYGQVPYPGMHSREVIENIERGFRMPKPTNHYFPDNIYQLLLQCWD 521
            ||:|||||||:||||.||.|.|:||||||::|||:|.:|||:||..|.:  .|.::::|::|||.
Zfish   501 KFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYRMQCPQD--CPSSLHELMVQCWK 563

  Fly   522 AVPEKRPTFEFLNHYFESFSVTSEVPYR 549
            ...|:|||||:|..:.|.:...:|..|:
Zfish   564 KDAEERPTFEYLQAFLEDYFTATEPQYQ 591

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Src64B	NP_001286937.1	SH2_Src_family	158..259	CDD:199827	52/100 (52%)
		PTKc_Src_like	289..538	CDD:270630	146/300 (49%)
		SH3_Src_like	99..150	CDD:212779	26/50 (52%)
fynb	XP_068071652.2	None