Protein Alignment Src64B and abl2

DIOPT Version :9

• Sequence 1: NP_001286937.1
• Gene: Src64B / 48973
• FlyBaseID: FBgn0262733
• Length: 553
• Species: Drosophila melanogaster
• Sequence 2: XP_005166946.1
• Gene: abl2 / 570636
• ZFINID: ZDB-GENE-020809-2
• Length: 1182
• Species: Danio rerio
• Alignment Length: 555
• Identity: 205/555 - (36%)
• Similarity: 306/555 - (55%)
• Gaps: 63/555 - (11%)

  Fly    31 GQTHINSSGG-----GNMGG-----VLGQKHNNGGSLDSRYTPDPNHRGPLKIGGKGGVDIIRPR 85
            |:::..||.|     |..||     :.|.......:......|||            |:::....
Zfish    27 GRSNRASSSGRRPRDGGGGGSSTLTLTGTPPGRSAAAAVNIMPDP------------GINVFTLH 79

  Fly    86 T----TPTGVPGVVLKRVV-------------------VALYDYKSRDESDLSFMKGDRMEVIDD 127
            :    .|.|:....|...|                   |||||:.:..::.||..||:::.|:..
Zfish    80 SEALHRPFGLDSTALTEAVRWSSKENLLGAAESDPNLFVALYDFVASGDNTLSITKGEKLRVLGY 144

  Fly   128 TESDWWRVVNLTTRQEGLIPLNFVAEERSVNSEDWFFENVLRKEADKLLLAEENPRGTFLVRPSE 192
            .::..|..|. :...:|.:|.|::....|:....|:...|.|..|:.||.:..|  |:||||.||
Zfish   145 NQNGEWSEVR-SKNGQGWVPSNYITPVNSLEKHSWYHGPVSRSAAEYLLSSLIN--GSFLVRESE 206

  Fly   193 HNPNGYSLSVKDWEDGRGYHVKHYRIKPLDNGGYYIATNQTFPSLQALVMAYSKENALGLCHILS 257
            .:|...|:|::  .:||.|   ||||....:|..|:.....|.:|..||..:|.. |.||...|.
Zfish   207 SSPGQLSISLR--YEGRVY---HYRINTASDGKVYVTAESRFSTLAELVHHHSTV-ADGLVTTLH 265

  Fly   258 RPCPK-PQPQMWDLGPELRDKYEIPRSEIQLLRKLGRGNFGEVFYGKWRN-SIDVAVKTLREGTM 320
            .|.|| .:|.::.:.| :.||:|:.|::|.:..|||.|.:|||:.|.|:. ::.||||||:|.||
Zfish   266 YPAPKCNKPTVYGVSP-IHDKWEMERTDITMKHKLGGGQYGEVYVGVWKKYNLTVAVKTLKEDTM 329

  Fly   321 STAAFLQEAAIMKKFRHNRLVALYAVCSQEEPIYIVQEYMSKGSLLDFLREGDGRYLHFEDLIYI 385
            ....||:||::||:.:|..||.|..||:.|.|.|||.|||..|:|||:|||.:...::...|:|:
Zfish   330 EVEEFLKEASVMKEVKHPNLVQLLGVCTLEPPFYIVTEYMPHGNLLDYLRECERDQVNAVVLLYM 394

  Fly   386 ATQVASGMEYLESKQLIHRDLAARNVLIGENNVAKICDFGLARVIADDEYCPKQGSRFPVKWTAP 450
            |||::|.|||||.|..|||||||||.|:|||:|.|:.||||:|::..|.|....|::||:|||||
Zfish   395 ATQISSAMEYLEKKNFIHRDLAARNCLVGENHVVKVADFGLSRLMTGDTYTAHAGAKFPIKWTAP 459

  Fly   451 EAIIYGKFSIKSDVWSYGILLMELFTYGQVPYPGMHSREVIENIERGFRMPKPTNHYFPDNIYQL 515
            |::.|..||||||||::|:||.|:.|||..||||:...:|.:.:|:|:||.:|..  .|..:|:|
Zfish   460 ESLAYNTFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYDLLEKGYRMEQPEG--CPPKVYEL 522

  Fly   516 LLQCWDAVPEKRPTFEFLNHYFESF----SVTSEV 546
            :..||...|..||:|..::..||:.    |::.||
Zfish   523 MRACWQWSPLDRPSFAEIHQAFETMFHDSSISEEV 557

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Src64B	NP_001286937.1	SH3_Src_like	99..150	CDD:212779	15/69 (22%)
		SH2_Src_family	158..259	CDD:199827	35/100 (35%)
		STYKc	285..537	CDD:214568	124/252 (49%)
		PTKc_Src_like	289..538	CDD:270630	123/249 (49%)
abl2	XP_005166946.1	SH3_Abl	116..169	CDD:212784	15/53 (28%)
		SH2_ABL	174..267	CDD:198189	35/100 (35%)
		PTKc_Abl	286..548	CDD:270645	128/263 (49%)
		Pkinase_Tyr	293..544	CDD:285015	124/252 (49%)
		FABD	1057..1182	CDD:197885

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000006
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X88
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.910