DRSC/TRiP Functional Genomics Resources

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Protein Alignment Src64B and grapb

DIOPT Version :10

Sequence 1:NP_001286937.1 Gene:Src64B / 48973 FlyBaseID:FBgn0262733 Length:553 Species:Drosophila melanogaster
Sequence 2:NP_001025251.2 Gene:grapb / 555184 ZFINID:ZDB-GENE-050913-4 Length:214 Species:Danio rerio


Alignment Length:168 Identity:53/168 - (31%)
Similarity:85/168 - (50%) Gaps:25/168 - (14%)


- Green bases have known domain annotations that are detailed below.


  Fly   102 ALYDYKSRDESDLSFMKGDRMEVID-DTESDWWRVVNLTTRQEGLIPLNFVAEERSVNSEDWFFE 165
            |||.:::.:..:|||.||:.::|.: |.:.:|:....|..|  |.:|.|::    :|....||..
Zfish     5 ALYSFRATECDELSFQKGEILKVTNMDDDPNWYTAELLGRR--GYVPKNYI----NVRPHTWFVG 63

  Fly   166 NVLRKEADKLLLAEENPRGTFLVRPSEHNPNGYSLSVKDWEDGRGYHVKHYRIKPLDNG-GYYIA 229
            .:.|:.|:..|...|  .|.||:|.||..|..:|:||     ..|.||:|:::  |.:| |.|..
Zfish    64 GISRQAAENRLRPLE--CGAFLIRESESTPGEFSVSV-----SYGDHVQHFKV--LKDGLGQYFI 119

  Fly   230 TNQTFPSLQALVMAY-----SKENALGLCH---ILSRP 259
            .::.|.||..||..|     :||..:.|..   .|:||
Zfish   120 WDEVFSSLNQLVDFYRINSIAKERTVFLREPEGSLARP 157

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Src64BNP_001286937.1 SH2_Src_family 158..259 CDD:199827 34/109 (31%)
PTKc_Src_like 289..538 CDD:270630
SH3_Src_like 99..150 CDD:212779 15/48 (31%)
grapbNP_001025251.2 SH3 2..55 CDD:473055 16/55 (29%)
SH2_Grb2_like 56..149 CDD:199828 33/101 (33%)
SH3 159..211 CDD:473055
Blue background indicates that the domain is not in the aligned region.

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