DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Src64B and grapa

DIOPT Version :9

Sequence 1:	NP_001286937.1	Gene:	Src64B / 48973	FlyBaseID:	FBgn0262733	Length:	553	Species:	Drosophila melanogaster
Sequence 2:	NP_001018409.1	Gene:	grapa / 553596	ZFINID:	ZDB-GENE-050522-347	Length:	214	Species:	Danio rerio

Alignment Length:	194	Identity:	58/194 - (29%)
Similarity:	91/194 - (46%)	Gaps:	25/194 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly   101 VALYDYKSRDESDLSFMKGDRMEVIDDTESDWWRVVNLTTRQEGLIPLNFVAEERSVNSEDWFFE 165
            ||||::.:.:..:|||.|||.:::.:..:...|.......| :|.:|.|::    |:....||..
Zfish     4 VALYNFCATESDELSFQKGDVLKITNMEDDPNWYTAEFVNR-KGYVPKNYI----SLRPHAWFAG 63

  Fly   166 NVLRKEADKLLLAEENPRGTFLVRPSEHNPNGYSLSVKDWEDGRGYHVKHYRIKPLDNGGYYIAT 230
            .:.|..|:..|  .:...|:||||.||..|..:|:||     ..|.||:|:::.. |..|||...
Zfish    64 RISRHVAENRL--HQRDCGSFLVRESESAPGEFSMSV-----SYGDHVQHFKVLK-DREGYYFVW 120

  Fly   231 NQTFPSLQALVMAYSKENALG---------LCHILSRPCPKPQPQMWDLGPELRDKYEIPRSEI 285
            .:.||||..||..| |.|::.         |.|.|.|  |.....::|..||...:....|.::
Zfish   121 EEIFPSLNQLVDFY-KTNSIAKERTVFLRDLDHTLKR--PHHAHALFDFNPEHNSQLHFLRGDV 181

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Src64B	NP_001286937.1	SH3_Src_like	99..150	CDD:212779	14/48 (29%)
		SH2_Src_family	158..259	CDD:199827	36/109 (33%)
		STYKc	285..537	CDD:214568	0/1 (0%)
		PTKc_Src_like	289..538	CDD:270630
grapa	NP_001018409.1	SH3	2..55	CDD:302595	15/55 (27%)
		SH2_Grb2_like	56..149	CDD:199828	33/101 (33%)
		SH3_GRB2_like_C	159..211	CDD:212739	4/23 (17%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000006
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910