DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Src64B and grap2a

DIOPT Version :9

Sequence 1:	NP_001286937.1	Gene:	Src64B / 48973	FlyBaseID:	FBgn0262733	Length:	553	Species:	Drosophila melanogaster
Sequence 2:	NP_001017756.1	Gene:	grap2a / 550452	ZFINID:	ZDB-GENE-050417-275	Length:	284	Species:	Danio rerio

Alignment Length:	178	Identity:	55/178 - (30%)
Similarity:	91/178 - (51%)	Gaps:	31/178 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   104 YDYKSRDESDLSFMKGDRMEVIDDTESDWWRVVNLTTRQEGLIPLNFVAEERSVNSEDWFFENVL 168
            ||:....|.:|||.|||.:::: .::.||::..  ....||.:|.|:|  :|.:.|  ||.|:..
Zfish     7 YDFSGTAEDELSFRKGDTLKIL-GSQDDWFKAE--LHGHEGYVPKNYV--DRQIPS--WFKESAS 64

  Fly   169 RKEADKLLLAEENPRGTFLVRPSEHNPNGYSLSVKDWEDGRGYHVKHYRIKPLDNGGYYIATNQT 233
            |..|::.|::.|  .|.||:|.|:.:|..:|:||:     ..|.|:|:::....:|.||:.| :.
Zfish    65 RGSAEETLMSRE--VGAFLIRGSQSSPGDFSISVR-----HDYDVQHFKVMKDKSGHYYLWT-EK 121

  Fly   234 FPSLQALVMAY-----SKENALGLCH-----------ILSRPCPKPQP 265
            |.||..||..|     ||:..:.|..           |.|:|..:|.|
Zfish   122 FTSLNKLVDFYKTTSISKQKEIFLRDGSGDEPRAPPPIKSQPEVRPPP 169

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Src64B	NP_001286937.1	SH3_Src_like	99..150	CDD:212779	14/45 (31%)
		SH2_Src_family	158..259	CDD:199827	35/116 (30%)
		STYKc	285..537	CDD:214568
		PTKc_Src_like	289..538	CDD:270630
grap2a	NP_001017756.1	SH3_GRAP2_N	2..53	CDD:212880	16/50 (32%)
		SH2_Grb2_like	54..147	CDD:199828	33/102 (32%)
		SH3_GRAP2_C	231..283	CDD:212883
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000006
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910