Protein Alignment Src64B and yes1

DIOPT Version :9

• Sequence 1: NP_001286937.1
• Gene: Src64B / 48973
• FlyBaseID: FBgn0262733
• Length: 553
• Species: Drosophila melanogaster
• Sequence 2: NP_001013288.2
• Gene: yes1 / 407620
• ZFINID: ZDB-GENE-050126-1
• Length: 546
• Species: Danio rerio
• Alignment Length: 583
• Identity: 271/583 - (46%)
• Similarity: 363/583 - (62%)
• Gaps: 76/583 - (13%)

  Fly     1 MGNKCCSKRQDQELALAYPTGGYKKSDYTFGQTHINSSGGGNMGGVLGQKHNNGGSLDSRYTPDP 65
            ||  |...::|:.     ||..| :.|.|      |.:.|.:||               .|.|||
Zfish     1 MG--CVKSKEDKG-----PTQKY-RPDPT------NPTPGSHMG---------------LYGPDP 36

  Fly    66 NH-------RGPLK-----------IGGKGGVDIIRPRTTPTG--------------VPGVVLKR 98
            ..       :||..           .||...|      .||.|              .||||...
Zfish    37 TQMGQSPALKGPTNNYNSRSSGLTPFGGSSSV------ITPFGGASSSFSTVAVNNPFPGVVTGG 95

  Fly    99 VV--VALYDYKSRDESDLSFMKGDRMEVIDDTESDWWRVVNLTTRQEGLIPLNFVAEERSVNSED 161
            |.  ||||||::|...||||.||||.::|::||.|||...::.|.|:|.||.|:||...|:.:|:
Zfish    96 VTFFVALYDYEARTSDDLSFSKGDRFQIINNTEGDWWEARSINTGQKGYIPSNYVAPADSIQAEE 160

  Fly   162 WFFENVLRKEADKLLLAEENPRGTFLVRPSEHNPNGYSLSVKDWEDGRGYHVKHYRIKPLDNGGY 226
            |:|..:.||:|::|||...|.|||||||.||.....||||::||::.:|.:||||:|:.||:|||
Zfish   161 WYFGKMGRKDAERLLLLPGNQRGTFLVRESETTKGAYSLSIRDWDEMKGDNVKHYKIRKLDSGGY 225

  Fly   227 YIATNQTFPSLQALVMAYSKENALGLCHILSRPCPKPQPQMWDLGPELRDKYEIPRSEIQLLRKL 291
            ||.|...|.:||.||..|: |:|.|||:.|:..||..:||...|.   :|.:||||..::|..||
Zfish   226 YITTRAQFDTLQKLVKHYT-EHADGLCYRLTTVCPTVKPQTQGLA---KDAWEIPRESLRLELKL 286

  Fly   292 GRGNFGEVFYGKWRNSIDVAVKTLREGTMSTAAFLQEAAIMKKFRHNRLVALYAVCSQEEPIYIV 356
            |:|.||||:.|.|..:..||:|||:.||||..||||||.||||.||::||.||||.| |||||||
Zfish   287 GQGCFGEVWMGTWNGTTKVAIKTLKPGTMSPEAFLQEAQIMKKLRHDKLVPLYAVVS-EEPIYIV 350

  Fly   357 QEYMSKGSLLDFLREGDGRYLHFEDLIYIATQVASGMEYLESKQLIHRDLAARNVLIGENNVAKI 421
            .|||.||||||||:||:|:||....|:.:|.|:|.||.::|....|||||.|.|:|:|:|.|.||
Zfish   351 TEYMGKGSLLDFLKEGEGKYLKLPQLVDMAAQIADGMAFIERMNYIHRDLRAANILVGDNLVCKI 415

  Fly   422 CDFGLARVIADDEYCPKQGSRFPVKWTAPEAIIYGKFSIKSDVWSYGILLMELFTYGQVPYPGMH 486
            .||||||:|.|:||..:||::||:|||||||.:||:|:|||||||:||||.||.|.|:||||||.
Zfish   416 ADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMV 480

  Fly   487 SREVIENIERGFRMPKPTNHYFPDNIYQLLLQCWDAVPEKRPTFEFLNHYFESFSVTSEVPYR 549
            :|||:|.:|||:|||.|..  .|:::::::..||...|::|||||::..:.|.:...:|..|:
Zfish   481 NREVLEQVERGYRMPCPQG--CPESLHEMMRLCWKKEPDERPTFEYIQSFLEDYFTATEPQYQ 541

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Src64B	NP_001286937.1	SH3_Src_like	99..150	CDD:212779	27/52 (52%)
		SH2_Src_family	158..259	CDD:199827	51/100 (51%)
		STYKc	285..537	CDD:214568	147/251 (59%)
		PTKc_Src_like	289..538	CDD:270630	146/248 (59%)
yes1	NP_001013288.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..58		19/85 (22%)
		SH3_Yes	97..154	CDD:212940	29/56 (52%)
		SH2_Src_family	157..256	CDD:199827	51/99 (52%)
		PTKc_Yes	267..545	CDD:270654	156/281 (56%)
		Pkinase_Tyr	280..529	CDD:285015	147/251 (59%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	106	1.000	Domainoid score	I6487
eggNOG	1	0.900	-	-		E2759_KOG0197
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D248674at33208
OrthoFinder	1	1.000	-	-		FOG0000006
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100661
Panther	1	1.100	-	-	O	PTHR24418
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	10	9.780