Protein Alignment Src64B and fyna

DIOPT Version :9

• Sequence 1: NP_001286937.1
• Gene: Src64B / 48973
• FlyBaseID: FBgn0262733
• Length: 553
• Species: Drosophila melanogaster
• Sequence 2: NP_001315092.1
• Gene: fyna / 373872
• ZFINID: ZDB-GENE-030903-5
• Length: 537
• Species: Danio rerio
• Alignment Length: 570
• Identity: 274/570 - (48%)
• Similarity: 368/570 - (64%)
• Gaps: 59/570 - (10%)

  Fly     1 MGNKCCSKRQ------DQELALAYPTGGYKKSDYT------FGQTHIN---------SSGGGNMG 44
            ||...|..::      ::|.:::...|....||.|      ||.|.|.         |.|....|
Zfish     1 MGCVQCKDKEATKLTDERETSVSQHAGYRYGSDPTPQHYPSFGVTAIPNYNNFHAPVSQGVTVFG 65

  Fly    45 GVLGQKHNNGGSLDSRYTPDPNHRGPLKIGGKGGVDIIRPRTTPTGVPGVVLKRVVVALYDYKSR 109
            ||....|:  |:|.||                ||          |||      .:.||||||::|
Zfish    66 GVNSSSHS--GTLRSR----------------GG----------TGV------TLFVALYDYEAR 96

  Fly   110 DESDLSFMKGDRMEVIDDTESDWWRVVNLTTRQEGLIPLNFVAEERSVNSEDWFFENVLRKEADK 174
            .|.||||.||::.::::.||.|||...:|||...|.||.|:||...|:.:|||:|..:.||:|::
Zfish    97 SEDDLSFRKGEKFQILNSTEGDWWEARSLTTGGTGYIPSNYVAPVDSIQAEDWYFGKLGRKDAER 161

  Fly   175 LLLAEENPRGTFLVRPSEHNPNGYSLSVKDWEDGRGYHVKHYRIKPLDNGGYYIATNQTFPSLQA 239
            .||:..|||||||:|.||.....||||::||::.:|.|||||:|:.||||||||.|...|.:||.
Zfish   162 QLLSNGNPRGTFLIRESETTKGAYSLSIQDWDETKGDHVKHYKIRKLDNGGYYITTRAQFETLQQ 226

  Fly   240 LVMAYSKENALGLCHILSRPCPKPQPQMWDLGPELRDKYEIPRSEIQLLRKLGRGNFGEVFYGKW 304
            ||..|| ..|.|||..|..||.|..|::.||..:.:|.:||||..:||:::||.|.||||:.|.|
Zfish   227 LVHHYS-ARAAGLCCRLIVPCHKGMPRLADLSVKTKDVWEIPRESLQLIKRLGNGQFGEVWMGTW 290

  Fly   305 RNSIDVAVKTLREGTMSTAAFLQEAAIMKKFRHNRLVALYAVCSQEEPIYIVQEYMSKGSLLDFL 369
            ..:..||||||:.||||..:||:||.||||.||::||.||||.| |||||||.||||||||||||
Zfish   291 NGNTKVAVKTLKPGTMSPESFLEEAQIMKKLRHDKLVQLYAVVS-EEPIYIVTEYMSKGSLLDFL 354

  Fly   370 REGDGRYLHFEDLIYIATQVASGMEYLESKQLIHRDLAARNVLIGENNVAKICDFGLARVIADDE 434
            ::|:||.|...:|:.:|.|||:||.|:|....|||||.:.|:|:|::.|.||.||||||:|.|:|
Zfish   355 KDGEGRGLKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANILVGDSLVCKIADFGLARLIEDNE 419

  Fly   435 YCPKQGSRFPVKWTAPEAIIYGKFSIKSDVWSYGILLMELFTYGQVPYPGMHSREVIENIERGFR 499
            |..:||::||:|||||||.:||:|:|||||||:||||.||.|.|:||||||::|||:|.:|||:|
Zfish   420 YTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYR 484

  Fly   500 MPKPTNHYFPDNIYQLLLQCWDAVPEKRPTFEFLNHYFESFSVTSEVPYR 549
            ||.|.:  .|.::::|:||||...||:|||||:|..:.|.:...:|..|:
Zfish   485 MPCPQD--CPSSLHELMLQCWKRDPEERPTFEYLQAFLEDYFTATEPQYQ 532

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Src64B	NP_001286937.1	SH3_Src_like	99..150	CDD:212779	25/50 (50%)
		SH2_Src_family	158..259	CDD:199827	53/100 (53%)
		STYKc	285..537	CDD:214568	151/251 (60%)
		PTKc_Src_like	289..538	CDD:270630	149/248 (60%)
fyna	NP_001315092.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	13..34		3/20 (15%)
		SH3_Fyn_Yrk	85..140	CDD:212939	27/54 (50%)
		SH2_Src_Fyn_isoform_a_like	145..245	CDD:198281	53/100 (53%)
		PTKc_Fyn	261..534	CDD:270655	159/275 (58%)
		Pkinase_Tyr	271..520	CDD:285015	151/251 (60%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	106	1.000	Domainoid score	I6487
eggNOG	1	0.900	-	-		E2759_KOG0197
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D248674at33208
OrthoFinder	1	1.000	-	-		FOG0000006
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100661
Panther	1	1.100	-	-	O	PTHR24418
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	9	8.780