DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Src64B and CG10702

DIOPT Version :9

Sequence 1:	NP_001286937.1	Gene:	Src64B / 48973	FlyBaseID:	FBgn0262733	Length:	553	Species:	Drosophila melanogaster
Sequence 2:	NP_001188841.1	Gene:	CG10702 / 35181	FlyBaseID:	FBgn0032752	Length:	946	Species:	Drosophila melanogaster

Alignment Length:	276	Identity:	54/276 - (19%)
Similarity:	93/276 - (33%)	Gaps:	67/276 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   125 IDDTESDWWRVVNLTT--RQEGLIPLNFVAEERSVNSEDWFFENVLRKEADKLLLAEENPRGTFL 187
            :||.:.|...||.|.|  ..|       ..|.....||..:.:..|......||...:....:..
  Fly   538 LDDLQPDTRYVVLLRTFGNDE-------AHEAYEARSELTYVQTELDIPKPPLLELVKKTDSSLT 595

  Fly   188 VRPSEHNPNGYSLSVKDWEDGRGY-HVKHYRIKPLDNGGYYIATNQTFPSLQALVMAYSKENALG 251
            |:.:.|:...:.|:|.:..|.:.| ..::|..:|     .|:..:...|..    |||...:.
  Fly   596 VQMASHDHVSFLLTVFELSDDQDYIEQRNYCHQP-----SYVWQDMDGPRW----MAYEDYDD-- 649

  Fly   252 LCHILSRPCPKPQPQMWD--LGPELRDKYEIPRSEIQLLRKLGRGNFGEVFYGKWRNSIDVAVKT 314
             |      |.:...|..|  ...::|::|.....:.:..|:|..              .:|::..
  Fly   650 -C------CAQKAEQFEDSRFIADMREQYRCTLDDREQCRRLAH--------------TEVSLPQ 693

  Fly   315 LREGTMSTAAFLQEAAIMKKFRHNRLVALYAV---------CSQEEPIYIVQEYMSKGSLLD--- 367
            ||....:|.   .|...:.::|      |||:         ||....:|....|.....||.
  Fly   694 LRLPGNTTE---YELKALHRYR------LYALQLQACNPLGCSSHTTLYGRTNYTMGADLLTQLY 749

  Fly   368 --FLREGDGRYLHFED 381
              .:.|.|...:.||:
  Fly   750 ACHIPEMDKYIMRFEE 765

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Src64B	NP_001286937.1	SH3_Src_like	99..150	CDD:212779	8/26 (31%)
		SH2_Src_family	158..259	CDD:199827	19/101 (19%)
		STYKc	285..537	CDD:214568	21/111 (19%)
		PTKc_Src_like	289..538	CDD:270630	21/107 (20%)
CG10702	NP_001188841.1	Recep_L_domain	47..159	CDD:279382
		Furin-like	171..297	CDD:279142
		FU	210..258	CDD:238021
		Recep_L_domain	328..441	CDD:279382
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45468364
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930