Protein Alignment Src64B and Srms

DIOPT Version :9

• Sequence 1: NP_001286937.1
• Gene: Src64B / 48973
• FlyBaseID: FBgn0262733
• Length: 553
• Species: Drosophila melanogaster
• Sequence 2: NP_035611.3
• Gene: Srms / 20811
• MGIID: 101865
• Length: 507
• Species: Mus musculus
• Alignment Length: 439
• Identity: 197/439 - (44%)
• Similarity: 271/439 - (61%)
• Gaps: 19/439 - (4%)

  Fly    98 RVVVALYDYKSRDESDLSFMKGDRMEVIDDTESDWWRVVNLT-TRQEGLIPLNFVAE--ERSVNS 159
            |:..||||:.:|...:||..:|||:..:.: |.|:.....|: ....||:|:.::|:  ....:.
Mouse    69 RLFRALYDFTARCAEELSVSRGDRLYALKE-EGDYIFAQRLSGPPSTGLVPVTYLAKATPEPPSD 132

  Fly   160 EDWFFENVLRKEADKLLLAEENPRGTFLVRPSEHNPNGYSLSVKDWEDGRGYHVKHYRIKPLDNG 224
            :.|:|..:.|.:|.:|||:..|..|.||:||||.:..||||||:     ....|.||||....:|
Mouse   133 QPWYFSGISRAQAQQLLLSPANAPGAFLIRPSESSIGGYSLSVR-----AQAKVCHYRICMAPSG 192

  Fly   225 GYYIATNQTFPSLQALVMAYSKENALGLCHILSRPCPKPQPQMWDLGPELRDKYEIPRSEIQLLR 289
            ..|:...|.||||.|| :||.|.|...:.:.|.:||   .||:    |.::|::|.||||..|.|
Mouse   193 SLYLQEGQLFPSLDAL-LAYYKTNWKLIQNPLLQPC---IPQI----PLVQDEWERPRSEFVLRR 249

  Fly   290 KLGRGNFGEVFYGKWRNSIDVAVKTLREGTMSTAAFLQEAAIMKKFRHNRLVALYAVCSQEEPIY 354
            |||.|.||||:.|.|..||.||||.::...|..|...:|...:|..||.||:.|:|:||..||:|
Mouse   250 KLGEGFFGEVWEGLWLGSIPVAVKVIKSADMKLADLTKEIEALKSLRHERLIRLHAICSLGEPVY 314

  Fly   355 IVQEYMSKGSLLDFLREGDGRYLHFEDLIYIATQVASGMEYLESKQLIHRDLAARNVLIGENNVA 419
            ||.|.|.||:|..:|...:|:.|....|:..|.|||.||.|||.::::||||||||||:|::...
Mouse   315 IVTELMGKGNLQVYLGSSEGKALSLPHLLGFACQVAEGMSYLEERRVVHRDLAARNVLVGDDLTC 379

  Fly   420 KICDFGLARVIADDEYCPKQGSRFPVKWTAPEAIIYGKFSIKSDVWSYGILLMELFTYGQVPYPG 484
            |:.||||||::.||.|.|..||:.|||||||||..|..||.||||||:||||.|:|||||.||.|
Mouse   380 KVADFGLARLLKDDVYSPSSGSKIPVKWTAPEAANYRVFSQKSDVWSFGILLYEVFTYGQCPYEG 444

  Fly   485 MHSREVIENIERGFRMPKPTNHYFPDNIYQLLLQCWDAVPEKRPTFEFL 533
            |.:.|.::.|.||:|:|:|.  ..|..:|.|:::||...||:||||..|
Mouse   445 MTNHETLQQISRGYRLPRPA--VCPAEVYVLMVECWKGSPEERPTFAIL 491

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Src64B	NP_001286937.1	SH3_Src_like	99..150	CDD:212779	16/51 (31%)
		SH2_Src_family	158..259	CDD:199827	40/100 (40%)
		STYKc	285..537	CDD:214568	128/249 (51%)
		PTKc_Src_like	289..538	CDD:270630	127/245 (52%)
Srms	NP_035611.3	SH3	70..124	CDD:302595	16/54 (30%)
		SH2_Srm	134..212	CDD:198223	36/83 (43%)
		PTKc_Srm_Brk	238..498	CDD:133248	133/256 (52%)
		STYKc	246..495	CDD:214568	128/248 (52%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0197
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D248674at33208
OrthoFinder	1	1.000	-	-		FOG0000006
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.820