DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Src64B and Grap2

DIOPT Version :9

Sequence 1:	NP_001286937.1	Gene:	Src64B / 48973	FlyBaseID:	FBgn0262733	Length:	553	Species:	Drosophila melanogaster
Sequence 2:	NP_001276371.1	Gene:	Grap2 / 17444	MGIID:	1333842	Length:	322	Species:	Mus musculus

Alignment Length:	143	Identity:	45/143 - (31%)
Similarity:	80/143 - (55%)	Gaps:	15/143 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly   102 ALYDYKSRDESDLSFMKGDRMEVIDDTESDWWRVVNLTTRQEGLIPLNFVAEERSVNSEDWFFEN 166
            |.:|:.:..|.:|||..||.::::.:.|.  |....|.: |||.:|.||:    .:...:||.|.
Mouse     5 AKFDFMASGEDELSFRTGDILKILSNQEE--WLKAELGS-QEGYVPKNFI----DIEFPEWFHEG 62

  Fly   167 VLRKEADKLLLAEENPRGTFLVRPSEHNPNGYSLSVKDWEDGRGYHVKHYRIKPLDNGGYYIATN 231
            :.|.:|:.||:.::  .|.|::|.|:.:|..:|:||:..:|     |:|:::.....|.|::.|
Mouse    63 LSRHQAENLLMGKD--IGFFIIRASQSSPGDFSISVRHEDD-----VQHFKVMRDTKGNYFLWT- 119

  Fly   232 QTFPSLQALVMAY 244
            :.||||..||..|
Mouse   120 EKFPSLNKLVDYY 132

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Src64B	NP_001286937.1	SH3_Src_like	99..150	CDD:212779	15/47 (32%)
		SH2_Src_family	158..259	CDD:199827	28/87 (32%)
		STYKc	285..537	CDD:214568
		PTKc_Src_like	289..538	CDD:270630
Grap2	NP_001276371.1	SH3	2..53	CDD:302595	17/54 (31%)
		SH2_Grb2_like	54..147	CDD:199828	28/87 (32%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	143..216
		SH3_GRAP2_C	267..319	CDD:212883
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000006
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910