Protein Alignment Src64B and dlk-1

DIOPT Version :10

• Sequence 1: NP_001286937.1
• Gene: Src64B / 48973
• FlyBaseID: FBgn0262733
• Length: 553
• Species: Drosophila melanogaster
• Sequence 2: NP_001021443.1
• Gene: dlk-1 / 173128
• WormBaseID: WBGene00001008
• Length: 928
• Species: Caenorhabditis elegans
• Alignment Length: 308
• Identity: 91/308 - (29%)
• Similarity: 137/308 - (44%)
• Gaps: 49/308 - (15%)

  Fly   262 KPQPQMWDLGPELRDKYEIPRSEIQLLRKLGRGNFGEVFYGKWRNSIDVAVKTLREGTMSTAAFL 326
            |.:.::|          |||...|..|..||.|:.|.||.|:..|. .||||.:.:        |
 Worm   122 KSEDELW----------EIPFDAISELEWLGSGSQGAVFRGQLENR-TVAVKKVNQ--------L 167

  Fly   327 QEAAI--MKKFRHNRLVALYAVCSQEEPIYIVQEYMSKGSLLDFLREGDGRYLHFEDLIYIATQV 389
            :|..|  ::..||..::....|||:.....||.||.|||.|...|:..:  .:..|.......::
 Worm   168 KETEIKHLRHLRHQNIIEFLGVCSKSPCYCIVMEYCSKGQLCTVLKSRN--TITRELFAQWVKEI 230

  Fly   390 ASGMEYLESKQLIHRDLAARNVLIGENNVAKICDFGLARVIADDE-----YCPKQGSRFPVKWTA 449
            |.||.||...::|||||.:.|:||...:..||||||.:.:....:     :|   |:   |.|.|
 Worm   231 ADGMHYLHQNKVIHRDLKSPNILISAEDSIKICDFGTSHMQKKMDSTMMSFC---GT---VSWMA 289

  Fly   450 PEAIIYGKFSIKSDVWSYGILLMELFTYGQVPYPGMHSREVIENIERG-FRMPKPTNHYFPDNIY 513
            ||.|.....:.|.||:|:|::|.|:.| .:.||..:....:|..:... ..:|.|..  .|..:.
 Worm   290 PEMIKKQPCNEKVDVYSFGVVLWEMLT-RETPYANIAQMAIIFGVGTNILSLPMPEE--APKGLV 351

  Fly   514 QLLLQCWDAVPEKRPTFEFLNHYF-----ESFSVTSEV------PYRE 550
            .|:.||.......||:|..:..::     |.|.:|.|.      .|||
 Worm   352 LLIKQCLSQKGRNRPSFSHIRQHWEIFKPELFEMTEEEWQLAWDSYRE 399

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Src64B	NP_001286937.1	SH2_Src_family	158..259	CDD:199827
		PTKc_Src_like	289..538	CDD:270630	77/261 (30%)
		SH3_Src_like	99..150	CDD:212779
dlk-1	NP_001021443.1	Protein Kinases, catalytic domain	141..377	CDD:473864	77/255 (30%)