DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Src64B and LOC101733045

DIOPT Version :9

Sequence 1:	NP_001286937.1	Gene:	Src64B / 48973	FlyBaseID:	FBgn0262733	Length:	553	Species:	Drosophila melanogaster
Sequence 2:	XP_031757813.1	Gene:	LOC101733045 / 101733045	-ID:	-	Length:	568	Species:	Xenopus tropicalis

Alignment Length:	522	Identity:	186/522 - (35%)
Similarity:	270/522 - (51%)	Gaps:	44/522 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    38 SGGG--NMGGVLGQKHNNGGSLDSRYTPDPNHRGPLKIGGKGGVDIIRPRTTPTGVPGVVLKRVV 100
            ||.|  |.|.|...:.:|...::.:...:|.|..|    .:..|.::.|:.         |.|..
Frog    73 SGQGKENPGFVPQDELDNPMRMEPQLIHEPQHPSP----EQPSVGVLHPKQ---------LSRAA 124

  Fly   101 -VALYDYKSRDESDLSFMKGDRMEVIDDTESDWWRVVNLTTR---QEGLIPLNFVAEERSVNSED 161
             |::|.|.:|....:...:|||:||| .|:..|..|...|.|   |...||.:|:|:..|:.:||
Frog   125 KVSMYSYTARSPGGMDVQRGDRLEVI-GTKGPWVLVQRETGRGPAQTCYIPKSFLADAGSLEAED 188

  Fly   162 WFFENVLRKEADKLLLAEENPRGTFLVRPSEHNPNGYSLSVKDWEDGRGYHVKHYRIKPLDNGGY 226
            |:|..:.|.:|.:.||.|.|..|:|||   .|:...|.|||:..:.     |:||||... .|.|
Frog   189 WYFGGIRRMDAKRFLLQEPNGSGSFLV---WHSDASYWLSVRVEQT-----VRHYRITQA-QGAY 244

  Fly   227 YIATNQTFPSLQALVMAYSKENALGLCHILSRPCP-KPQPQMWDLGPELRDKYEIPRSEIQLLRK 290
            |:.....|.:|.|||:.|.:::. |||..|.:||. ...|:|..|.....|:.||..:.|:.:||
Frog   245 YLVERAAFRTLGALVLYYQQQSD-GLCTRLGKPCVWLDVPRMPSLCHTAVDQLEISPNSIERIRK 308

  Fly   291 LGRGNFGEVFYGKWRNSIDVAVKTLREGTMSTAAFLQ-----EAAIMKKFRHNRLVALYAVCSQE 350
            ||||:||.|:.|||..:..||:|.|:    .||..||     ||..|.|..|.||:.|||||.|.
Frog   309 LGRGSFGLVWLGKWNGTTQVAIKELQ----VTAQSLQKSLYGEADTMWKLSHERLLKLYAVCLQV 369

  Fly   351 EPIYIVQEYMSKGSLLDFLRE-GDGRYLHFEDLIYIATQVASGMEYLESKQLIHRDLAARNVLIG 414
            .|::||.|||.:|:|..:||: ...|.|..:.|:..|.|:..||.|:|....:||||.|.|:|:.
Frog   370 SPVFIVTEYMERGTLKRYLRDHQQNRNLELQQLMDFAAQICQGMGYMEQNLCVHRDLRAENILLS 434

  Fly   415 ENNVAKICDFGLARVIADDEYCPKQGSRFPVKWTAPEAIIYGKFSIKSDVWSYGILLMELFTYGQ 479
            .....||.||||||.:..........:|.|:||.|||.....::|.||||||:|:||:|:.|||:
Frog   435 AMLSCKIGDFGLARFMDSSSIAMSADARIPIKWMAPEVFSEQRYSSKSDVWSFGVLLVEIVTYGK 499

  Fly   480 VPYPGMHSREVI-ENIERGFRMPKPTNHYFPDNIYQLLLQCWDAVPEKRPTFEFLNHYFESFSVT 543
            :|:|.:.:.:.: |.:..|..:..|.:  .|||:..::..||......||||..|..........
Frog   500 MPFPEITNEQYVREMLREGGTLQPPRD--APDNVSYIMNMCWRRAAPTRPTFAELERLIMDLLTF 562

  Fly   544 SE 545
            ||
Frog   563 SE 564

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Src64B	NP_001286937.1	SH3_Src_like	99..150	CDD:212779	18/54 (33%)
		SH2_Src_family	158..259	CDD:199827	37/100 (37%)
		STYKc	285..537	CDD:214568	104/258 (40%)
		PTKc_Src_like	289..538	CDD:270630	103/255 (40%)
LOC101733045	XP_031757813.1	SH2	185..276	CDD:417686	37/100 (37%)
LOC101733045	XP_031757813.1	STYKc	303..556	CDD:214568	104/258 (40%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D539311at2759
OrthoFinder	1	1.000	-	-		FOG0000006
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010