DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Src64B and grap2

DIOPT Version :9

Sequence 1:	NP_001286937.1	Gene:	Src64B / 48973	FlyBaseID:	FBgn0262733	Length:	553	Species:	Drosophila melanogaster
Sequence 2:	XP_002933793.1	Gene:	grap2 / 100492322	XenbaseID:	XB-GENE-6086850	Length:	301	Species:	Xenopus tropicalis

Alignment Length:	208	Identity:	57/208 - (27%)
Similarity:	107/208 - (51%)	Gaps:	32/208 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   102 ALYDYKSRDESDLSFMKGDRMEVIDDTESDWWRVVNLTTRQEGLIPLNFVAEERSVNSEDWFFEN 166
            |:|::.:..|.:|||.|||.:::: .::.:|::  :.....||.:|.|:|    .|:...|:.||
Frog     5 AMYEFNASGEDELSFKKGDVLKIL-SSDDNWYK--SELNGSEGYVPKNYV----EVHFPRWYCEN 62

  Fly   167 VLRKEADKLLLAEENPRGTFLVRPSEHNPNGYSLSVKDWEDGRGYHVKHYRIKPLDNGGYYIATN 231
            :.|.||:.:|:...  .|.|::|.|:.:...:|:||:|.:|     |:|:::.....|.||:.|
Frog    63 ISRGEAESILIGRF--VGAFIIRASQTSKGEFSMSVRDEDD-----VQHFKVMRDIRGNYYLWT- 119

  Fly   232 QTFPSLQALVMAYSKENALGLCHILSRPCPKPQPQMW--DLGPELRDKYEIPRSEIQLLRKLGRG 294
            :.|.||..||..|...:       :||     |.:::  :.|.|.::|  :....::..|..|.|
Frog   120 EKFKSLNKLVEYYKTAS-------ISR-----QKEIYLREEGSEAQEK--LVEKHVRDPRSSGGG 170

  Fly   295 NFGEVF-YGKWRN 306
            ..|::. .|..||
Frog   171 RAGKLMPAGSQRN 183

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Src64B	NP_001286937.1	SH3_Src_like	99..150	CDD:212779	13/47 (28%)
		SH2_Src_family	158..259	CDD:199827	29/100 (29%)
		STYKc	285..537	CDD:214568	7/23 (30%)
		PTKc_Src_like	289..538	CDD:270630	7/19 (37%)
grap2	XP_002933793.1	SH3_GRAP2_N	2..53	CDD:212880	15/54 (28%)
		SH2_Grb2_like	54..147	CDD:199828	31/112 (28%)
		SH3_GRAP2_C	246..298	CDD:212883
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000006
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000