Protein Alignment Src64B and abl1

DIOPT Version :10

• Sequence 1: NP_001286937.1
• Gene: Src64B / 48973
• FlyBaseID: FBgn0262733
• Length: 553
• Species: Drosophila melanogaster
• Sequence 2: XP_002936228.2
• Gene: abl1 / 100490771
• XenbaseID: XB-GENE-6054675
• Length: 1128
• Species: Xenopus tropicalis
• Alignment Length: 452
• Identity: 186/452 - (41%)
• Similarity: 283/452 - (62%)
• Gaps: 18/452 - (3%)

  Fly   101 VALYDYKSRDESDLSFMKGDRMEVIDDTESDWWRVVNLTTRQEGLIPLNFVAEERSVNSEDWFFE 165
            |||||:.:..::.||..||:::.|:....:..|.... |...:|.:|.|::....|.....|:..
 Frog    94 VALYDFVASGDNTLSITKGEKLRVLGYNHNGEWCEAQ-TKNGQGWVPSNYITPVNSPEKHSWYHG 157

  Fly   166 NVLRKEADKLLLAEENPRGTFLVRPSEHNPNGYSLSVKDWEDGRGYHVKHYRIKPLDNGGYYIAT 230
            .|.|..|:.||.:..|  |:||||.||.:|...|:|::  .:||.|   ||||....:|..|:::
 Frog   158 PVSRNAAEYLLSSGIN--GSFLVRESESSPGQRSISLR--YEGRVY---HYRINTASDGKLYVSS 215

  Fly   231 NQTFPSLQALVMAYSKENALGLCHILSRPCPK-PQPQMWDLGPELRDKYEIPRSEIQLLRKLGRG 294
            :..|.:|..||..:|..:. ||...|..|.|| .:|.::.:.|.. ||:||.|::|.:..|||.|
 Frog   216 DSRFNTLAELVHHHSTVSD-GLITTLHYPAPKRNKPTIYGVSPNY-DKWEIERTDITMKHKLGGG 278

  Fly   295 NFGEVFYGKWRN-SIDVAVKTLREGTMSTAAFLQEAAIMKKFRHNRLVALYAVCSQEEPIYIVQE 358
            .:|||:.|.|:. ::.||||||:|.||....||:|||:||:.:|..||.|..||::|.|.||:.|
 Frog   279 QYGEVYEGVWKKYNLTVAVKTLKEDTMEVEEFLKEAAVMKEVKHPNLVQLLGVCTREPPFYIITE 343

  Fly   359 YMSKGSLLDFLREGDGRYLHFEDLIYIATQVASGMEYLESKQLIHRDLAARNVLIGENNVAKICD 423
            :|:.|:|||:||:.:.:.:....|:::|||::|.|||||.|..|||||||||.|:|||::.|:.|
 Frog   344 FMTYGNLLDYLRDCNRQEVTAVVLLHMATQISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVAD 408

  Fly   424 FGLARVIADDEYCPKQGSRFPVKWTAPEAIIYGKFSIKSDVWSYGILLMELFTYGQVPYPGMHSR 488
            |||:|::..|.|....|::||:||||||::.|.|||||||||::|:||.|:.|||..||||:...
 Frog   409 FGLSRLMTGDTYTAHAGAKFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLS 473

  Fly   489 EVIENIERGFRMPKPTNHYFPDNIYQLLLQCWDAVPEKRPTFEFLNHYFESF----SVTSEV 546
            :|.|.:|:.:||.:|..  .|:.:|:|:.:||...|..||:|..::..||:.    |::.||
 Frog   474 QVYELLEKDYRMERPEG--CPEKVYELMRECWQWSPLDRPSFAEIHQDFETMFQESSISDEV 533

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Src64B	NP_001286937.1	SH2_Src_family	158..259	CDD:199827	34/100 (34%)
		PTKc_Src_like	289..538	CDD:270630	120/249 (48%)
		SH3_Src_like	99..150	CDD:212779	14/48 (29%)
abl1	XP_002936228.2	SH3_Abl	92..145	CDD:212784	15/51 (29%)
		SH2_ABL	150..243	CDD:198189	34/100 (34%)
		PTKc_Abl	262..524	CDD:270645	126/263 (48%)
		F_actin_bind	1003..1128	CDD:471692