DRSC/TRiP Functional Genomics Resources

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Protein Alignment Src64B and grap

DIOPT Version :10

Sequence 1:NP_001286937.1 Gene:Src64B / 48973 FlyBaseID:FBgn0262733 Length:553 Species:Drosophila melanogaster
Sequence 2:NP_001332868.1 Gene:grap / 100127598 XenbaseID:XB-GENE-6258733 Length:219 Species:Xenopus tropicalis


Alignment Length:148 Identity:45/148 - (30%)
Similarity:80/148 - (54%) Gaps:12/148 - (8%)


- Green bases have known domain annotations that are detailed below.


  Fly   102 ALYDYKSRDESDLSFMKGDRMEVIDDTESDWWRVVNLTTRQEGLIPLNFVAEERSVNSEDWFFEN 166
            |:|::|:.:..:|.|.|||.:::::..:...|....|..| ||.||.|::    .|....|:...
 Frog     5 AIYNFKTTERDELPFKKGDIIKILNMEDDQNWFKAELFGR-EGYIPKNYI----KVKPHPWYAGR 64

  Fly   167 VLRKEADKLLLAEENPRGTFLVRPSEHNPNGYSLSVKDWEDGRGYHVKHYRI-KPLDNGGYYIAT 230
            :.|:.|:::|| :.|..|.||:|.||.:|..:|:||     ..|:||:|::: :..::.|.|...
 Frog    65 ISRQVAEEILL-KRNFVGAFLIRDSESSPGDFSISV-----NYGHHVQHFKVLRDTESNGKYYLW 123

  Fly   231 NQTFPSLQALVMAYSKEN 248
            ...|.||..||..|.:.:
 Frog   124 EAKFNSLNELVDYYRRHS 141

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Src64BNP_001286937.1 SH2_Src_family 158..259 CDD:199827 28/92 (30%)
PTKc_Src_like 289..538 CDD:270630
SH3_Src_like 99..150 CDD:212779 15/47 (32%)
grapNP_001332868.1 SH3_GRAP_N 2..55 CDD:212881 16/54 (30%)
SH2_Grb2_like 56..152 CDD:199828 28/92 (30%)
SH3_GRAP_C 161..213 CDD:212884
Blue background indicates that the domain is not in the aligned region.

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