DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Src64B and grap

DIOPT Version :9

Sequence 1:	NP_001286937.1	Gene:	Src64B / 48973	FlyBaseID:	FBgn0262733	Length:	553	Species:	Drosophila melanogaster
Sequence 2:	NP_001332868.1	Gene:	grap / 100127598	XenbaseID:	XB-GENE-6258733	Length:	219	Species:	Xenopus tropicalis

Alignment Length:	148	Identity:	45/148 - (30%)
Similarity:	80/148 - (54%)	Gaps:	12/148 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly   102 ALYDYKSRDESDLSFMKGDRMEVIDDTESDWWRVVNLTTRQEGLIPLNFVAEERSVNSEDWFFEN 166
            |:|::|:.:..:|.|.|||.:::::..:...|....|..| ||.||.|::    .|....|:...
Frog     5 AIYNFKTTERDELPFKKGDIIKILNMEDDQNWFKAELFGR-EGYIPKNYI----KVKPHPWYAGR 64

  Fly   167 VLRKEADKLLLAEENPRGTFLVRPSEHNPNGYSLSVKDWEDGRGYHVKHYRI-KPLDNGGYYIAT 230
            :.|:.|:::|| :.|..|.||:|.||.:|..:|:||     ..|:||:|::: :..::.|.|...
Frog    65 ISRQVAEEILL-KRNFVGAFLIRDSESSPGDFSISV-----NYGHHVQHFKVLRDTESNGKYYLW 123

  Fly   231 NQTFPSLQALVMAYSKEN 248
            ...|.||..||..|.:.:
Frog   124 EAKFNSLNELVDYYRRHS 141

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Src64B	NP_001286937.1	SH3_Src_like	99..150	CDD:212779	15/47 (32%)
		SH2_Src_family	158..259	CDD:199827	28/92 (30%)
		STYKc	285..537	CDD:214568
		PTKc_Src_like	289..538	CDD:270630
grap	NP_001332868.1	SH3_GRAP_N	2..55	CDD:212881	16/54 (30%)
		SH2_Grb2_like	56..152	CDD:199828	28/92 (30%)
		SH3_GRAP_C	161..213	CDD:212884
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000006
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910