Protein Alignment Atpalpha and mgtA

DIOPT Version :9

• Sequence 1: NP_732572.1
• Gene: Atpalpha / 48971
• FlyBaseID: FBgn0002921
• Length: 1041
• Species: Drosophila melanogaster
• Sequence 2: NP_418663.1
• Gene: mgtA / 948778
• ECOCYCID: EG12525
• Length: 898
• Species: Escherichia coli
• Alignment Length: 1051
• Identity: 286/1051 - (27%)
• Similarity: 475/1051 - (45%)
• Gaps: 218/1051 - (20%)

  Fly    38 RKMPAKVNKKENLDDLKQELD------IDFH----KISP-EELYQRFQTHPENGLSHAKAKENLE 91
            |.:|:::..::.|...:|.::      :..|    .:.| |||::.|.|||| ||:.|:.:...|
E. coli    11 RHLPSRLVHRDPLPGAQQTVNTVVPPSLSAHCLKMAVMPEEELWKTFDTHPE-GLNQAEVESARE 74

  Fly    92 RDGPNALTPPKQTPEWVKFCKNLFGGFAMLLWIGAILCFVAYSIQASTSEEPADDNLYLGIVLSA 156
            :.|.|.|...:.:|.||.........|.:||   .||..::|          |.::|:...|::.
E. coli    75 QHGENKLPAQQPSPWWVHLWVCYRNPFNILL---TILGAISY----------ATEDLFAAGVIAL 126

  Fly   157 VVIVTGIFSYYQESKSSKIMESFKNMVPQFATVIR----EGEK--LTLRAEDLVLGDVVEVKFGD 215
            :|.::.:.::.||::|:|..::.|.||...|||:|    :||.  |.:..:.||.||::::..||
E. coli   127 MVAISTLLNFIQEARSTKAADALKAMVSNTATVLRVINDKGENGWLEIPIDQLVPGDIIKLAAGD 191

  Fly   216 RIPADIRIIEARNFKVDNSSLTGESEPQSRGA---EFTHENPLETKNLAFFSTNAVEGTAKGVVI 277
            .||||:||::||:..|..:||||||.|..:.|   :..|.||||...|.|..|..|.|||:.:||
E. coli   192 MIPADLRILQARDLFVAQASLTGESLPVEKAATTRQPEHSNPLECDTLCFMGTTVVSGTAQAMVI 256

  Fly   278 SCGDHTVMGRIAGLASGLDTGETPIAKEIHHFIHLITGVAVFLGVTFF-----VIAFILGY---H 334
            :.|.:|..|::||..|..::       |.:.|...|:.|::.| :.|.     |:..|.||   .
E. coli   257 ATGANTWFGQLAGRVSEQES-------EPNAFQQGISRVSMLL-IRFMLVMAPVVLLINGYTKGD 313

  Fly   335 WLDAVIFLIGIIVANVPEGLLATVTVCLTLTAKRMASKNCLVKNLEAVETLGSTSTICSDKTGTL 399
            |.:|.:|.:.:.|...||.|...||..|...|.:::.:..:||:|:|::..|:...:|:||||||
E. coli   314 WWEAALFALSVAVGLTPEMLPMIVTSTLARGAVKLSKQKVIVKHLDAIQNFGAMDILCTDKTGTL 378

  Fly   400 TQNRMTVAHMWFDNQIIEADTTEDQSGVQYDRT----------SPGFKALSRIATLCNRAEFKGG 454
            ||:::          ::|..|  |.||...:|.          ..|.|.|...|.|
E. coli   379 TQDKI----------VLENHT--DISGKTSERVLHSAWLNSHYQTGLKNLLDTAVL--------- 422

  Fly   455 QDGVPILKKEVSGDASEAALLKCMELALGDVMNIRKRNKKIAEVPFNSTNKYQVSIHETEDTNDP 519
                       .|...|:|            .::..|.:||.|:||:...: ::|:...|:|.
E. coli   423 -----------EGTDEESA------------RSLASRWQKIDEIPFDFERR-RMSVVVAENTE-- 461

  Fly   520 RYLLVMKGAPERILERCSTIFINGKEKVLDEEMKEAFNNAYMELGGLGERVLGFCDFMLPSDKYP 584
            .:.||.|||.:.||..||.:..||:...||:.|..........|...|.||:......||:.:
E. coli   462 HHQLVCKGALQEILNVCSQVRHNGEIVPLDDIMLRKIKRVTDTLNRQGLRVVAVATKYLPARE-- 524

  Fly   585 NGFKFNTDDINFPIDNLRFVGLMSMIDPPRAAVPDAVAKCRSAGIKVIMVTGDHPITAKAIAKSV 649
             |.....|:     .:|...|.::.:|||:.....|:...:::||.|.::|||..:.|..:...|
E. coli   525 -GDYQRADE-----SDLILEGYIAFLDPPKETTAPALKALKASGITVKILTGDSELVAAKVCHEV 583

  Fly   650 GIISEGNETVEDIAQRLNIPVSEVNPREAKAAVVHGAELRDVSSDQLDEILRYHTEIVFARTSPQ 714
            |:         |..:                 ||.|:::..:|.|:|..:.:..|  :|||.:|.
E. coli   584 GL---------DAGE-----------------VVIGSDIETLSDDELANLAQRTT--LFARLTPM 620

  Fly   715 QKLIIVEGCQRMGAIVAVTGDGVNDSPALKKADIGVAMGIAGSDVSKQAADMILLDDNFASIVTG 779
            .|..||...:|.|.:|...|||:||:|||:.||||:::. ...|::::|||:|||:.:...:..|
E. coli   621 HKERIVTLLKREGHVVGFMGDGINDAPALRAADIGISVD-GAVDIAREAADIILLEKSLMVLEEG 684

  Fly   780 VEEGRLIFDNLKKSIAYTLTSNIPEI------SPFLAFILCDIPLPLGTVTILCIDLGTDMVPAI 838
            |.|||..|.|:.|.|..|.:||...:      |.||.|      ||:..:.:|..:|..| |..:
E. coli   685 VIEGRRTFANMLKYIKMTASSNFGNVFSVLVASAFLPF------LPMLPLHLLIQNLLYD-VSQV 742

  Fly   839 SLAYEHAEADIMKRPPR-DPFNDKLVNSRLISMAYGQIGMIQAAAGFFVYFVIMAENGFLP-KKL 901
            ::.:::.:.:.:::|.| :|                      |..|.|:.|       |.| ..:
E. coli   743 AIPFDNVDDEQIQKPQRWNP----------------------ADLGRFMIF-------FGPISSI 778

  Fly   902 FGIRK---MWDSKAVNDLTDSYGQEWTYR----DRKTLEYTCHTAFFISIVVVQWADLIICKTRR 959
            |.|..   ||               |.:.    :.:||   ..:.:|:..::.|...:.:.:|||
E. coli   779 FDILTFCLMW---------------WVFHANTPETQTL---FQSGWFVVGLLSQTLIVHMIRTRR 825

  Fly   960 NSIFQQGMRNWALNFGLVFETVLAAFLSYCP-GMEKGLRMYPLKLVWWFPAIPFALAIFIYDETR 1023
            .. |.|...:|.|....|...::...|.:.| .....|:..||....|..|| .|..:.:....:
E. coli   826 VP-FIQSCASWPLMIMTVIVMIVGIALPFSPLASYLQLQALPLSYFPWLVAI-LAGYMTLTQLVK 888

  Fly  1024 RFYLRRNPGGW 1034
            .||.||.  ||
E. coli   889 GFYSRRY--GW 897

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Atpalpha	NP_732572.1	ATPase-IIC_X-K	45..1041	CDD:273445	284/1044 (27%)
		Cation_ATPase_N	58..132	CDD:214842	25/84 (30%)
		E1-E2_ATPase	152..383	CDD:278548	84/247 (34%)
		Cation_ATPase	445..539	CDD:289987	22/93 (24%)
		COG4087	<695..770	CDD:226572	30/74 (41%)
		Cation_ATPase_C	817..1025	CDD:279079	41/217 (19%)
mgtA	NP_418663.1	PRK10517	1..898	CDD:236705	286/1051 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	67	1.000	Domainoid score	I532
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	282	1.000	Inparanoid score	I96
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000283
OrthoInspector	1	1.000	-	-		otm51342
orthoMCL	1	0.900	-	-		OOG6_100215
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
	7	6.860