Protein Alignment Atpalpha and SPF1

DIOPT Version :9

• Sequence 1: NP_732572.1
• Gene: Atpalpha / 48971
• FlyBaseID: FBgn0002921
• Length: 1041
• Species: Drosophila melanogaster
• Sequence 2: NP_010883.3
• Gene: SPF1 / 856681
• SGDID: S000000757
• Length: 1215
• Species: Saccharomyces cerevisiae
• Alignment Length: 1132
• Identity: 233/1132 - (20%)
• Similarity: 403/1132 - (35%)
• Gaps: 324/1132 - (28%)

  Fly    70 YQRFQTHPENGLSHAKAKENLERDGPNALTPPKQTPEWVKFCKN-------LFGGFAMLLWIGAI 127
            :|:.:.| ...|:|.|     ...|.|:...|  .|.:::..|.       :|..|.:.||:  :
Yeast   160 FQKCKGH-SGDLTHLK-----RLYGENSFDIP--IPTFMELFKEHAVAPLFVFQVFCVALWL--L 214

  Fly   128 LCFVAYSIQASTSEEPADDNLYLGIVLSAVVIVTGIFSYYQESKSSKIMESFKNM--VPQFATVI 190
            ..|..||:          .||::.|.:.|..:...:.:          ::.|:.|  .|....|.
Yeast   215 DEFWYYSL----------FNLFMIISMEAAAVFQRLTA----------LKEFRTMGIKPYTINVF 259

  Fly   191 REGEKLTLRAEDLVLGDVVEV---KFGDRIPADIRIIEARNFKVDNSSLTGESEPQSRGAEFTHE 252
            |..:.:.|:..:|:..|:|.:   .....||.|:.:::.... |:.:.|:|||.|..:  |....
Yeast   260 RNKKWVALQTNELLPMDLVSITRTAEESAIPCDLILLDGSAI-VNEAMLSGESTPLLK--ESIKL 321

  Fly   253 NPLETKNLAFFSTNAV---EGTAKGVVISCGDHTV-------MGRIAGLA-SGLDTGETPIAKEI 306
            .|.| .||.....:.:   .|..|.:.::..:|..       .|.:|.:. :|.:|.:..:.:.:
Yeast   322 RPSE-DNLQLDGVDKIAVLHGGTKALQVTPPEHKSDIPPPPDGGALAIVTKTGFETSQGSLVRVM 385

  Fly   307 HHFIHLITGVAV-----FLGVTFFVIAFILG--YHWLDA----------VIFLIGIIVANVPEGL 354
               |:....|:|     .:.:.|.:|..::.  |.|::.          ::..|.||.:.||..|
Yeast   386 ---IYSAERVSVDNKEALMFILFLLIFAVIASWYVWVEGTKMGRIQSKLILDCILIITSVVPPEL 447

  Fly   355 LATVTVCLTLTAKRMASKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHMWFDNQIIEAD 419
            ...:|:.:..:...:|...........:...|.....|.|||||||...:..
Yeast   448 PMELTMAVNSSLAALAKFYVYCTEPFRIPFAGRIDVCCFDKTGTLTGEDLVF------------- 499

  Fly   420 TTEDQSGVQYDRTSPGFKALSRIATLCNRAEFKGG--------------QDGVPILKKEVSGDAS 470
              |..:|:..|.        ..|..|.:.||....              :||      ::.||..
Yeast   500 --EGLAGISADS--------ENIRHLYSAAEAPESTILVIGAAHALVKLEDG------DIVGDPM 548

  Fly   471 EAALLKCMELALGDVMNIRKRNKK--------IAEVPFNSTNKYQVSIHETEDTNDPRYLLVMKG 527
            |.|.||    |:|..:..:..|.:        |....|:|..|...||   ...||..:..| ||
Yeast   549 EKATLK----AVGWAVERKNSNYREGTGKLDIIRRFQFSSALKRSASI---ASHNDALFAAV-KG 605

  Fly   528 APERILERCSTIFINGKEKVLDEEMKEAFNNAYMELGGLGERVLGFCDFMLPSDKYPNGFKFNTD 592
            |||.|.||.|.|..|             ::..|......|.|||......||..........|.|
Yeast   606 APETIRERLSDIPKN-------------YDEIYKSFTRSGSRVLALASKSLPKMSQSKIDDLNRD 657

  Fly   593 DINFPIDNLRFVGLMSMIDPPRAAVPDAVAKCRSAGIKVIMVTGDHPITAKAIAKSVGII----- 652
            |:.   ..|.|.|.:....|.:....:.:.....:..:.||:|||:|:||..:||.|||:
Yeast   658 DVE---SELTFNGFLIFHCPLKDDAIETIKMLNESSHRSIMITGDNPLTAVHVAKEVGIVFGETL 719

  Fly   653 -------SEGNETV-EDIAQRLNIPV---------SEVNPREAKAAVVHGAELRDVSS-DQLDEI 699
                   |:.|:.: .|:.:.::||.         |::..|...|  |.|..|..:.. .||.::
Yeast   720 ILDRAGKSDDNQLLFRDVEETVSIPFDPSKDTFDHSKLFDRYDIA--VTGYALNALEGHSQLRDL 782

  Fly   700 LRYHTEIVFARTSPQQKLIIVEGCQRMGAIVAVTGDGVNDSPALKKADIGVAMGIAGSDVSKQAA 764
            || || .|:||.||.||..::...:.||....:.|||.||..|||:|.:|:|
Yeast   783 LR-HT-WVYARVSPSQKEFLLNTLKDMGYQTLMCGDGTNDVGALKQAHVGIA------------- 832

  Fly   765 DMILLDDNFASIVTGVEEG--------RLIFDNLK----KSIAYTLTSNIPE--ISPFLAFILCD 815
                       ::.|.|||        ||  :.:|    |...:....|.|:  :...:|.:.
Yeast   833 -----------LLNGTEEGLKKLGEQRRL--EGMKMMYIKQTEFMARWNQPQPPVPEPIAHLF-- 882

  Fly   816 IPLPLGTVTILCID-LGTDMVPAISLAYEHAEA---DIMK------RPPRD-------------- 856
            .|.|.....:..:: .||.:.|.|..|.|.|.:   :::|      :.|.|
Yeast   883 PPGPKNPHYLKALESKGTVITPEIRKAVEEANSKPVEVIKPNGLSEKKPADLASLLLNSAGDAQG 947

  Fly   857 ---------------PFNDKLVNSRLIS--MAYGQIGMIQA------------AAGFFVYFVIMA 892
                           ||..||.|...::  :..|:..::..            .:.:.:..:.||
Yeast   948 DEAPALKLGDASCAAPFTSKLANVSAVTNIIRQGRCALVNTIQMYKILALNCLISAYSLSIIYMA 1012

  Fly   893 ----------ENGFLPKKLF-------------------GIRKMW------DSKAVNDLTDSYGQ 922
                      .:|.|....|                   ||..::      ...||:..|..|..
Yeast  1013 GVKFGDGQATVSGLLLSVCFLSISRGKPLEKLSKQRPQSGIFNVYIMGSILSQFAVHIATLVYIT 1077

  Fly   923 EWTYR----------DRKTLEYTCHTAFFISIVVVQWADLIICKTRRNSIFQQGMR-NWALNFGL 976
            ...|:          :::......:|..||..:|.|.:...:  ..:...|::.:| |..:.:||
Yeast  1078 TEIYKLEPREPQVDLEKEFAPSLLNTGIFIIQLVQQVSTFAV--NYQGEPFRENIRSNKGMYYGL 1140

  Fly   977 VFET--VLAAFLSYCPGMEKGLRMYPL 1001
            :..|  .||:...:.|.:.:.::..|:
Yeast  1141 LGVTGLALASATEFLPELNEAMKFVPM 1167

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Atpalpha	NP_732572.1	ATPase-IIC_X-K	45..1041	CDD:273445	233/1132 (21%)
		Cation_ATPase_N	58..132	CDD:214842	15/68 (22%)
		E1-E2_ATPase	152..383	CDD:278548	47/263 (18%)
		Cation_ATPase	445..539	CDD:289987	32/115 (28%)
		COG4087	<695..770	CDD:226572	26/74 (35%)
		Cation_ATPase_C	817..1025	CDD:279079	45/286 (16%)
SPF1	NP_010883.3	P-type_ATPase_cation	169..1136	CDD:319843	224/1089 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910