Protein Alignment Atpalpha and PMA2

DIOPT Version :9

• Sequence 1: NP_732572.1
• Gene: Atpalpha / 48971
• FlyBaseID: FBgn0002921
• Length: 1041
• Species: Drosophila melanogaster
• Sequence 2: NP_015289.1
• Gene: PMA2 / 856071
• SGDID: S000005957
• Length: 947
• Species: Saccharomyces cerevisiae
• Alignment Length: 1031
• Identity: 252/1031 - (24%)
• Similarity: 428/1031 - (41%)
• Gaps: 235/1031 - (22%)

  Fly    22 ATDDDNRTADGQYKSRRKMPAKV---------NKKENLDDLKQELDIDF---------------- 61
            ::...:.|:.....|...:|.|.         :..|::|.|..||..::
Yeast    33 SSSSSSSTSTSASSSAAAVPRKAAAASAADDSDSDEDIDQLIDELQSNYGEGDESGEEEVRTDGV 97

  Fly    62 ---HKISPEELYQRFQTHPENGLSHAKAKENLERDGPNALTPPKQTPEWVKFCKNLFGGFAMLLW 123
               .::.||   :...|.|..||:..:.....::.|.|.:....:: ..|||.....|....::.
Yeast    98 HAGQRVVPE---KDLSTDPAYGLTSDEVARRRKKYGLNQMAEENES-LIVKFLMFFVGPIQFVME 158

  Fly   124 IGAILCFVAYSIQASTSEEPADDNLYLGIVLSAVVIVTGIFSYYQESKSSKIMESFKNMVPQFAT 188
            ..|||.       |..|     |.:.:| |:.|::::.....:.||.::..|::..|..:...||
Yeast   159 AAAILA-------AGLS-----DWVDVG-VICALLLLNASVGFIQEFQAGSIVDELKKTLANTAT 210

  Fly   189 VIREGEKLTLRAEDLVLGDVVEVKFGDRIPADIRIIEARNF-KVDNSSLTGESEPQSR--GAEFT 250
            |||:|:.:.:.|.::|.|::::::.|...|||.||:....| ::|.|::||||....:  |.|
Yeast   211 VIRDGQLIEIPANEVVPGEILQLESGTIAPADGRIVTEDCFLQIDQSAITGESLAAEKHYGDE-- 273

  Fly   251 HENPLETKNLAFFSTNAVEGTAKGVVISCGDHTVMGRIA---GLASGLDTGETPIAKEIHHFIHL 312
                      .|.|:....|.|..||.:.||:|.:||.|   |.|||::          .||..:
Yeast   274 ----------VFSSSTVKTGEAFMVVTATGDNTFVGRAAALVGQASGVE----------GHFTEV 318

  Fly   313 ITGVAVFLGVTFFVIAFIL------GYHWLDAVIFL---IGIIVANVPEGLLATVTVCLTLTAKR 368
            :.|:.:.|.|  .|||.:|      .|..:..|..|   :||.:..||.||.|.||..:.:.|..
Yeast   319 LNGIGIILLV--LVIATLLLVWTACFYRTVGIVSILRYTLGITIIGVPVGLPAVVTTTMAVGAAY 381

  Fly   369 MASKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHMWFDNQIIEADTTEDQSGVQYDRTS 433
            :|.|..:|:.|.|:|:|.....:|||||||||:|:::: |        |..|.|   ||..|
Yeast   382 LAKKQAIVQKLSAIESLAGVEILCSDKTGTLTKNKLSL-H--------EPYTVE---GVSPD--- 431

  Fly   434 PGFKALSRIATLCNRAEFKGGQDGVPILKKEVSGDASEAALLKCMELALGDVMNIRKRNKKIAEV 498
                  ..:.|.|..|.           :|:...||.:.|.||.: :......:...:.|.:...
Yeast   432 ------DLMLTACLAAS-----------RKKKGLDAIDKAFLKSL-IEYPKAKDALTKYKVLEFH 478

  Fly   499 PFNSTNKYQVSIHETEDTNDPRYLLVMKGAPERILERCSTIFINGKEKVLDEEMKEAFNNAYMEL 563
            ||:..:|...::.|:.   :...::.:||||..:|:...      ::..:.|::.|.:.|...||
Yeast   479 PFDPVSKKVTAVVESP---EGERIVCVKGAPLFVLKTVE------EDHPIPEDVHENYENKVAEL 534

  Fly   564 GGLGERVLGFCDFMLPSDKYPNGFKFNTDDINFPIDNLRFVGLMSMIDPPRAAVPDAVAKCRSAG 628
            ...|.|.||.      :.|...|             :...:|:|..:||||......:.:.|:.|
Yeast   535 ASRGFRALGV------ARKRGEG-------------HWEILGVMPCMDPPRDDTAQTINEARNLG 580

  Fly   629 IKVIMVTGDHPITAKAIAKSVGIISEGNETVEDIAQRLNIPVSEVNPREAKAAVVHGAELRDV-- 691
            :::.|:|||....||...:.:|:   |.....  |:||.:......|         |:||.|.
Yeast   581 LRIKMLTGDAVGIAKETCRQLGL---GTNIYN--AERLGLGGGGDMP---------GSELADFVE 631

  Fly   692 SSDQLDEILRYHTEIVFARTSPQQKLIIVEGCQRMGAIVAVTGDGVNDSPALKKADIGVAMGIAG 756
            ::|.            ||...||.|..:||..|..|.:||:|||||||:|:|||||.|:|:. ..
Yeast   632 NADG------------FAEVFPQHKYRVVEILQNRGYLVAMTGDGVNDAPSLKKADTGIAVE-GA 683

  Fly   757 SDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEISPFLAFILCDIPLPLG 821
            :|.::.|||::.|....::|:..::..|.||..:...:.|.:..:: .:..||...:..:...|.
Yeast   684 TDAARSAADIVFLAPGLSAIIDALKTSRQIFHRMYSYVVYRIALSL-HLEIFLGLWIAILNNSLD 747

  Fly   822 TVTILCIDLGTDMVPAISLAYEHAEADIMKRPPRDPFNDKLVNSRLISMAYGQIGMIQAAAGFFV 886
            ...|:.|.:..| |..:::||::|        |..|...|....||..|:. .:|::.|...:..
Yeast   748 INLIVFIAIFAD-VATLTIAYDNA--------PYAPEPVKWNLPRLWGMSI-ILGIVLAIGSWIT 802

  Fly   887 YFVIMAENGFLPKKLFGIRKMWDSKAVNDLTDSYGQEWTYRDRKTLEYTCHTAFFISIVVVQ-WA 950
            ...:...||.:.:. ||        |:|.:                       .|:.|.:.: |
Yeast   803 LTTMFLPNGGIIQN-FG--------AMNGV-----------------------MFLQISLTENW- 834

  Fly   951 DLIICKTRRNSIFQQGMRNWALNFGLVFETVLAAFLSYCPGMEKGLRMYPLKLVWW 1006
              :|..||....|...:.:|.| .|.||...:.|            .|:.| ..||
Yeast   835 --LIFVTRAAGPFWSSIPSWQL-AGAVFAVDIIA------------TMFTL-FGWW 874

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Atpalpha	NP_732572.1	ATPase-IIC_X-K	45..1041	CDD:273445	248/999 (25%)
		Cation_ATPase_N	58..132	CDD:214842	15/92 (16%)
		E1-E2_ATPase	152..383	CDD:278548	73/245 (30%)
		Cation_ATPase	445..539	CDD:289987	18/93 (19%)
		COG4087	<695..770	CDD:226572	30/74 (41%)
		Cation_ATPase_C	817..1025	CDD:279079	39/191 (20%)
PMA2	NP_015289.1	P-type_ATPase_H	116..903	CDD:319771	239/945 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910